{"id":"W4225000929","doi":"10.14740/wjon1464","title":"Hemophagocytic Lymphohistiocytosis Secondary to Immune Checkpoint Inhibitor Therapy","year":2022,"lang":"en","type":"review","venue":"World Journal of Oncology","topic":"Autoimmune and Inflammatory Disorders Research","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Nivolumab; Ipilimumab; Pembrolizumab; Immunotherapy; Hemophagocytic lymphohistiocytosis; Adverse effect; Internal medicine; Pediatrics; Immunology; Immune system; Disease","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008659451,0.0003000048,0.0008626698,0.001776571,0.0002198406,0.000641237,0.0003274488,0.0005784346,0.00113275],"category_scores_gemma":[0.003176724,0.0001676919,0.0007363822,0.002141002,0.0004472698,0.0006304769,0.0004215184,0.0003736754,0.0002145894],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004290385,"about_ca_system_score_gemma":0.0006266288,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003077836,"about_ca_topic_score_gemma":0.0004022591,"domain_scores_codex":[0.9992858,0.0002138184,0.0002295261,0.00008093179,0.0001277947,0.00006213172],"domain_scores_gemma":[0.9978127,0.001136385,0.0008169474,0.00007597099,0.0001060276,0.00005191385],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"case_report","study_design_scores_codex":[0.00091411,0.0001252181,0.08958632,0.07901181,0.0033352,0.3771587,0.001065052,0.0006885806,0.0106357,0.002914725,0.01264962,0.4219148],"study_design_scores_gemma":[0.0002435449,0.0005250936,0.07478701,0.02409838,0.002826589,0.7971428,0.00090503,0.0005098038,0.00745215,0.002546939,0.08890717,0.00005545334],"study_design_candidate":"case_report","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1952545,0.7834058,0.002348572,0.001118445,0.0003732668,0.0002872701,0.0007855308,0.00009830335,0.01632831],"genre_scores_gemma":[0.7452736,0.2493518,0.001003136,0.001734659,0.0009139376,0.000104186,0.0005366844,0.00001267651,0.001069225],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001776571,"threshold_uncertainty_score":0.004579663,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06882043454900784,"score_gpt":0.387105941612769,"score_spread":0.3182855070637611,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}