{"id":"W4225003254","doi":"10.1158/2326-6066.cir-21-0931","title":"Combination Neoantigen-Based Dendritic Cell Vaccination and Adoptive T-Cell Transfer Induces Antitumor Responses Against Recurrence of Hepatocellular Carcinoma","year":2022,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pancreas Centre (Canada)","funders":"","keywords":"Medicine; Immunotherapy; Adjuvant; CD8; Immune system; Immunology; T cell; Immunoediting; Hepatocellular carcinoma; Dendritic cell; Adjuvant therapy; Adoptive cell transfer; Oncology; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002685486,0.0003798536,0.0008089087,0.0002398766,0.0001016094,0.0002168124,0.0002412912,0.0002404553,0.0004450003],"category_scores_gemma":[0.0002088164,0.0001594402,0.0002648094,0.0001679423,0.0001917188,0.000165279,0.0002287471,0.0006322676,0.0001794633],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001966317,"about_ca_system_score_gemma":0.0002258892,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000188535,"about_ca_topic_score_gemma":0.0002907041,"domain_scores_codex":[0.9998037,0.00004193973,0.00002117871,0.00003574053,0.00004253556,0.00005491051],"domain_scores_gemma":[0.9999087,0.00001870623,0.00002003753,0.00001979657,0.000006993196,0.00002576681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006321593,0.005703795,0.003236348,0.0002332204,0.0001666114,0.0003198802,0.0001126458,0.002243663,0.8998053,0.0002043494,0.0004559988,0.08119658],"study_design_scores_gemma":[0.006527732,0.176647,0.03158495,0.00004506225,0.0007175005,0.0026209,0.00008189375,0.01657,0.7587411,0.0003247788,0.006097094,0.00004197861],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979758,0.0005951055,0.0009350317,0.00003236435,0.00002898895,0.00007718092,0.0000238192,0.00004130575,0.0002904098],"genre_scores_gemma":[0.9984897,0.0002652549,0.0008015445,0.00003883688,0.00003793759,0.00006172695,0.00007402813,0.000005852915,0.0002249689],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008089087,"threshold_uncertainty_score":0.001488686,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0460332441837773,"score_gpt":0.3094296325806096,"score_spread":0.2633963883968323,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}