{"id":"W4225109369","doi":"10.1371/journal.pmed.1003980","title":"Nonregistration, discontinuation, and nonpublication of randomized trials: A repeated metaresearch analysis","year":2022,"lang":"en","type":"article","venue":"PLoS Medicine","topic":"Meta-analysis and systematic reviews","field":"Decision Sciences","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; University of Toronto; McMaster University; Impact","funders":"Magyar Tudományos Akadémia; Bundesamt für Gesundheit; Albert-Ludwigs-Universität Freiburg; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Institute for Health and Care Research; University of Oxford; Universität Basel; Alexander von Humboldt-Stiftung; National Science Foundation","keywords":"Randomized controlled trial; Medicine; Discontinuation; Meta-analysis; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","insufficient_payload"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.5082096,0.0001710748,0.009217697,0.001649079,0.0002017987,0.0001633146,0.0008547095,0.0000293526,0.03716056],"category_scores_gemma":[0.4674423,0.00007433604,0.001610353,0.00612009,0.0002307849,0.0001690958,0.0001270478,0.0001415157,0.00002646298],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000247989,"about_ca_system_score_gemma":0.00007711598,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001224338,"about_ca_topic_score_gemma":0.00005654491,"domain_scores_codex":[0.8634687,0.09681305,0.02460568,0.001252768,0.01362335,0.0002364511],"domain_scores_gemma":[0.9030511,0.05924555,0.02463456,0.005750793,0.007008719,0.0003092757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0198275,0.002454025,0.1784914,0.0004523823,0.1393128,0.00002177867,0.0391367,0.002547317,0.01507832,0.07990259,0.4560944,0.06668068],"study_design_scores_gemma":[0.129817,0.0008754777,0.04594745,0.0001222909,0.09881582,0.00002299145,0.018973,0.6131774,0.0006115671,0.04182466,0.04897223,0.0008401244],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6423749,0.0141181,0.2328727,0.07939263,0.0003594057,0.01033491,0.0001609675,0.00003093236,0.0203555],"genre_scores_gemma":[0.9915562,0.00005820966,0.001047347,0.0001117619,0.00007042061,0.0003982963,0.0001610322,0.000005804063,0.006590902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6106301,"threshold_uncertainty_score":0.9637196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.8664424332281055,"score_gpt":0.593664555665147,"score_spread":0.2727778775629586,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}