{"id":"W4225109369","doi":"10.1371/journal.pmed.1003980","title":"Nonregistration, discontinuation, and nonpublication of randomized trials: A repeated metaresearch analysis","year":2022,"lang":"en","type":"article","venue":"PLoS Medicine","topic":"Meta-analysis and systematic reviews","field":"Decision Sciences","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; University of Toronto; McMaster University; Impact","funders":"Magyar Tudományos Akadémia; Bundesamt für Gesundheit; Albert-Ludwigs-Universität Freiburg; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Institute for Health and Care Research; University of Oxford; Universität Basel; Alexander von Humboldt-Stiftung; National Science Foundation","keywords":"Randomized controlled trial; Medicine; Discontinuation; Meta-analysis; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.3314951,0.003404603,0.01507058,0.01217399,0.001188286,0.006614337,0.005317902,0.003062259,0.003058818],"category_scores_gemma":[0.4446902,0.002288732,0.08329198,0.01334801,0.002316036,0.004865436,0.00416262,0.003405817,0.0005530585],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004721835,"about_ca_system_score_gemma":0.005305887,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003307694,"about_ca_topic_score_gemma":0.003992428,"domain_scores_codex":[0.5356526,0.329828,0.08547162,0.02070359,0.02602013,0.002324134],"domain_scores_gemma":[0.3659324,0.5022348,0.07050957,0.04811504,0.01199992,0.001208268],"domain_codex":null,"domain_gemma":"reporting","domain_candidate":"reporting","domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"observational","study_design_scores_codex":[0.003752887,0.00005495677,0.03434565,0.0599307,0.8864919,0.0001937105,0.0003646832,0.001251162,0.0002081485,0.0005571754,0.0008794357,0.01196959],"study_design_scores_gemma":[0.00284246,0.001040025,0.02545958,0.01333064,0.9454809,0.0003373893,0.0001831674,0.003478373,0.0007443671,0.00309019,0.003839566,0.000173515],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.08271334,0.8141779,0.08047216,0.002845018,0.00215758,0.009119133,0.005576302,0.0008044214,0.002134036],"genre_scores_gemma":[0.8651166,0.05637514,0.0541943,0.001877799,0.0008949789,0.0172663,0.002827726,0.0004558911,0.0009914113],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.668505,"threshold_uncertainty_score":0.8243856,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.8664424332281055,"score_gpt":0.593664555665147,"score_spread":0.2727778775629586,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}