{"id":"W4225130964","doi":"10.1002/pro.4296","title":"Synthetic antibodies block receptor binding and current‐inhibiting effects of α‐cobratoxin from <i>Naja kaouthia</i>","year":2022,"lang":"en","type":"article","venue":"Protein Science","topic":"Venomous Animal Envenomation and Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"European Research Council; European Commission; Villum Fonden","keywords":"Naja; Antibody; Molecular biology; Physics; Chemistry; Stereochemistry; Biology; Biochemistry; Immunology; Venom","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003378919,0.00009161123,0.0001207218,0.0000556628,0.0004863294,0.00002765467,0.0001857128,0.00001682877,0.000009334831],"category_scores_gemma":[0.0002749118,0.00008747698,0.00003172096,0.0001934234,0.000311189,0.0000071451,0.0004907507,0.00007731609,0.000003260606],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001332332,"about_ca_system_score_gemma":0.0000605645,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000018909,"about_ca_topic_score_gemma":0.000002292691,"domain_scores_codex":[0.9990474,0.00005429769,0.0001504255,0.0003363859,0.0002305154,0.0001809525],"domain_scores_gemma":[0.9996449,0.00001896024,0.0001120604,0.0001314332,0.000046627,0.00004602056],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001019818,0.00003171472,0.001071303,0.00004016383,0.000005540129,5.614827e-7,0.0002591959,0.000006032289,0.9960683,0.0001386987,0.00003459613,0.002333696],"study_design_scores_gemma":[0.000202862,0.000200295,0.0005996565,0.0000583718,0.000006727849,0.000003085912,0.0003533094,0.00009492667,0.9955856,0.0000602912,0.002705153,0.0001296946],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957813,0.00338343,0.00008134433,0.00007540175,0.0001142911,0.0002465924,0.0000347753,0.000009965298,0.0002728928],"genre_scores_gemma":[0.9990501,0.00006962468,0.0006958538,0.00002809635,0.00003443367,0.00004451625,0.000006562037,0.000006843211,0.00006390762],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003313806,"threshold_uncertainty_score":0.3740502,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008126074615636782,"score_gpt":0.237889964731626,"score_spread":0.2297638901159893,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}