{"id":"W4225259139","doi":"10.3390/mi13050730","title":"Microfluidic Platforms for the Isolation and Detection of Exosomes: A Brief Review","year":2022,"lang":"en","type":"review","venue":"Micromachines","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"","keywords":"Microvesicles; Extracellular vesicles; Exosome; Vesicle; Microfluidics; Nanoparticle tracking analysis; Isolation (microbiology); Nanotechnology; Cell biology; Computational biology; Chemistry; Biology; microRNA; Bioinformatics; Materials science; Membrane; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006602335,0.00133509,0.001268599,0.00331097,0.0002950997,0.001029514,0.0009066625,0.001226249,0.002803347],"category_scores_gemma":[0.0008126104,0.0005952292,0.0006808444,0.002458986,0.0003893406,0.001876573,0.0007135593,0.001424376,0.002353686],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005818548,"about_ca_system_score_gemma":0.001020345,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007101393,"about_ca_topic_score_gemma":0.0009371552,"domain_scores_codex":[0.999711,0.0000433098,0.00003981455,0.00006350235,0.0001163997,0.00002594827],"domain_scores_gemma":[0.9996197,0.000217424,0.00004390206,0.00001175546,0.00008558169,0.00002163539],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007195459,0.0001068074,0.0002196877,0.03053589,0.000108001,0.0002851989,0.00009443075,0.0007092959,0.01195981,0.007019954,0.02361215,0.9252769],"study_design_scores_gemma":[0.00001340169,0.0001776207,0.000615319,0.002408402,0.0001195914,0.001269556,0.00005133887,0.0002770784,0.004516008,0.001478487,0.9890253,0.00004803274],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001867659,0.9972504,0.0008087219,0.0001908756,0.0003106705,0.00001443994,0.00003638303,0.00002074569,0.001181135],"genre_scores_gemma":[0.0008088938,0.9971256,0.0008148987,0.0001636387,0.0002086767,0.00002290942,0.00006265355,0.00000371361,0.0007890334],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00331097,"threshold_uncertainty_score":0.009378135,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02671527184047459,"score_gpt":0.3102451842461658,"score_spread":0.2835299124056912,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}