{"id":"W4225266882","doi":"10.1097/pas.0000000000001909","title":"Endometrial Stromal Sarcomas With BCOR Internal Tandem Duplication and Variant BCOR/BCORL1 Rearrangements Resemble High-grade Endometrial Stromal Sarcomas With Recurrent CDK4 Pathway Alterations and MDM2 Amplifications","year":2022,"lang":"en","type":"article","venue":"The American Journal of Surgical Pathology","topic":"Uterine Myomas and Treatments","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University Health Network; University of Toronto; Markham Stouffville Hospital; Royal Jubilee Hospital; University of Calgary","funders":"","keywords":"Endometrial stromal sarcoma; Sarcoma; Angiosarcoma; Gene duplication; Medicine; Stromal cell; Oncology; Pathology; Cancer research; Internal medicine; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002825279,0.0002721998,0.0002489371,0.001151429,0.0002888776,0.0003553133,0.0001973857,0.0003025805,0.0009550792],"category_scores_gemma":[0.0009354656,0.000222917,0.0001778738,0.0006399296,0.0003494159,0.0002236749,0.0003844438,0.0001770275,0.0003031598],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002069777,"about_ca_system_score_gemma":0.0001537284,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007361987,"about_ca_topic_score_gemma":0.001727249,"domain_scores_codex":[0.999781,0.00003484747,0.00003506245,0.00004750269,0.00005418851,0.00004749468],"domain_scores_gemma":[0.9995468,0.00007374779,0.0002087008,0.0000553948,0.00003946437,0.00007578868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002798986,0.00003109442,0.923023,0.00007066365,0.00004312577,0.01576853,0.0003930109,0.0002708905,0.05019582,0.0001830001,0.0001272949,0.009613698],"study_design_scores_gemma":[0.00001991527,0.0001730854,0.8612753,0.00001318845,0.00003500857,0.1260693,0.0003582403,0.0007919821,0.009570218,0.0003429217,0.001338436,0.00001247207],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989997,0.0002166881,0.0003337919,0.000007339265,0.000001031729,0.00001163306,0.00008149849,0.000009021383,0.0003393035],"genre_scores_gemma":[0.9991844,0.0001144595,0.0004100591,0.000009243433,0.000003273016,0.000004175948,0.000141666,0.000002113452,0.0001306075],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001151429,"threshold_uncertainty_score":0.003195047,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0255058820286214,"score_gpt":0.2838734990340214,"score_spread":0.2583676170054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}