{"id":"W4225275791","doi":"10.1016/j.joen.2022.04.011","title":"Deciphering Stem Cell From Apical Papilla–Macrophage Choreography Using a Novel 3-dimensional Organoid System","year":2022,"lang":"en","type":"article","venue":"Journal of Endodontics","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; American Association of Endodontists Foundation","keywords":"Dentin sialophosphoprotein; Cell biology; Cytokine; Chemokine; M2 Macrophage; Dental pulp stem cells; Stromal cell; Macrophage inflammatory protein; Stem cell; Biology; Immunology; Chemistry; Interleukin; Macrophage; Inflammation; Cancer research; Pathology; Medicine; Odontoblast; Pulp (tooth)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006111105,0.0003252302,0.0003356081,0.0007199002,0.000428943,0.0009038937,0.0004209434,0.0006769436,0.001223106],"category_scores_gemma":[0.0003254709,0.000373879,0.0004714482,0.0003684205,0.0006370006,0.0007274616,0.0009052171,0.0009029519,0.00057319],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005139406,"about_ca_system_score_gemma":0.0007453776,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001539769,"about_ca_topic_score_gemma":0.003376052,"domain_scores_codex":[0.9997706,0.00003515527,0.00002067275,0.00005466359,0.000084214,0.00003471284],"domain_scores_gemma":[0.999626,0.0001232286,0.00005910422,0.00007242014,0.00006042084,0.00005876755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003515548,0.000007620283,0.0004858644,0.00005835983,0.000006164728,0.0001250804,0.00009140743,0.0003502145,0.9950433,0.0009307789,0.00006313464,0.002802907],"study_design_scores_gemma":[0.00001717288,0.0001031987,0.006182351,0.00002726317,0.00004987355,0.0008885943,0.0002363278,0.01025822,0.9680856,0.0006115472,0.01348723,0.00005261246],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7035168,0.004499927,0.2822905,0.0004250046,0.0002065947,0.0002105184,0.001318473,0.0007235856,0.006808523],"genre_scores_gemma":[0.7819558,0.002330843,0.2100739,0.0001464155,0.00003703587,0.0002323682,0.00100064,0.0001372749,0.004085809],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001539769,"threshold_uncertainty_score":0.00409174,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03686352267141249,"score_gpt":0.2736552304534825,"score_spread":0.23679170778207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}