{"id":"W4225299326","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a3243","title":"Role of Nuclear Factor-κB in the Regulation of IκB-kinase-ε and Interferon Regulatory Factor-1 Gene Expression in Human Pulmonary Epithelial Cells","year":2022,"lang":"en","type":"article","venue":"","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Interferon regulatory factors; Cancer research; Gene; Factor (programming language); Interferon; Cell biology; Biology; Transcription factor; Computer science; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002316447,0.0001145791,0.0001494348,0.0000883805,0.00005472247,0.000005455443,0.0002179932,0.00008953751,0.0001279805],"category_scores_gemma":[0.000008449805,0.00009666984,0.00004880293,0.00007975137,0.00007202957,0.000005536248,0.000238079,0.0001217122,3.438116e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002277428,"about_ca_system_score_gemma":0.00002123528,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007946634,"about_ca_topic_score_gemma":0.00002193301,"domain_scores_codex":[0.9989073,0.0002144805,0.0003013471,0.0002567967,0.0001882255,0.0001318932],"domain_scores_gemma":[0.9994774,0.0000160823,0.0001349572,0.0003270003,0.00002224015,0.00002224446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001339053,0.0001197462,0.002542317,0.00001801823,0.000004819774,0.000001379079,0.0007172266,0.000227253,0.9955787,0.00007217149,0.00003588727,0.0005485967],"study_design_scores_gemma":[0.0002988899,0.0003029599,0.04513758,0.00001406788,0.000002729625,0.000003328744,0.0007066634,0.000113972,0.9526687,0.0001893381,0.0004625779,0.0000992026],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990991,0.0002291643,0.00001678405,0.00001310304,0.00003293509,0.0001914771,0.00006061719,0.000004901572,0.0003519116],"genre_scores_gemma":[0.99964,0.00001169079,0.0001388086,0.0000313888,0.00002908083,0.000009780676,0.00005342442,0.00001861158,0.00006715389],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04290998,"threshold_uncertainty_score":0.3942081,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01052750276002195,"score_gpt":0.2182434648320705,"score_spread":0.2077159620720485,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}