{"id":"W4225330733","doi":"10.1099/mgen.0.000781","title":"An inventory of early branch points in microbial phosphonate biosynthesis","year":2022,"lang":"en","type":"article","venue":"Microbial Genomics","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Wilfrid Laurier University","funders":"Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Mutase; Biosynthesis; Phosphonate; Gene; Operon; Horizontal gene transfer; Biology; Enzyme; Biochemistry; Genome; Chemistry; Stereochemistry; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002771411,0.0001600448,0.0001960726,0.0001059648,0.00008573765,0.00001637182,0.0005316916,0.0001295304,0.0001199961],"category_scores_gemma":[0.00001759502,0.0001891402,0.0001327487,0.0001815986,0.0001283772,0.000004937124,0.0004539424,0.0002235207,0.00000738052],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005558991,"about_ca_system_score_gemma":0.0001620876,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001639488,"about_ca_topic_score_gemma":0.00003907023,"domain_scores_codex":[0.998621,0.0001611939,0.0002976833,0.000440189,0.0001210285,0.0003588558],"domain_scores_gemma":[0.9993742,0.000005528483,0.00008340691,0.0004063458,0.00003414161,0.00009633855],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005381819,0.0002778342,0.001065292,0.0000186323,0.00002900486,0.000006844309,0.0001410721,0.00006355903,0.9958659,0.00003334522,0.0005094105,0.001450884],"study_design_scores_gemma":[0.0007237598,0.000315168,0.0005817824,0.000004813308,0.000007177639,0.0000163395,0.00003292657,0.00001278438,0.9689209,0.00007253985,0.02910044,0.0002113111],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998713,0.000429895,0.00006242603,0.0001090131,0.0001347371,0.0002250342,0.0001583386,0.000007006988,0.0001605304],"genre_scores_gemma":[0.9983754,0.00007865322,0.0005413386,0.0004023513,0.00008257788,0.00001879697,0.0002155759,0.00004017076,0.0002452013],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02859103,"threshold_uncertainty_score":0.7712916,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009271039816025431,"score_gpt":0.2341320436444926,"score_spread":0.2248610038284671,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}