{"id":"W4225377973","doi":"10.1096/fasebj.2022.36.s1.r1963","title":"High Throughput Screening of Protein Arginine <i>N</i> ‐Methyltransferases – Filter Binding and Phosphor Screening (FBAPS) assay","year":2022,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria; University of British Columbia","funders":"","keywords":"Arginine; High-throughput screening; Methyltransferase; Chemistry; Ligand binding assay; Western blot; Enzyme; Biochemistry; Methylation; Amino acid; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001258786,0.001130638,0.00121805,0.0005628258,0.0003514882,0.0006929748,0.0009545635,0.0007310633,0.001718058],"category_scores_gemma":[0.0007455848,0.000433554,0.0008137337,0.0006966936,0.0003002632,0.0004311888,0.000455462,0.0008208702,0.001694738],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005561996,"about_ca_system_score_gemma":0.0004446586,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007751908,"about_ca_topic_score_gemma":0.001344161,"domain_scores_codex":[0.9987966,0.0003348634,0.00008915969,0.0002256858,0.0004504196,0.0001032103],"domain_scores_gemma":[0.9994918,0.0001782374,0.00009100891,0.00008252096,0.0001081169,0.00004825948],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000714269,0.00005832469,0.0002860558,0.00007783551,0.00002477513,0.00003672883,0.00001417763,0.0002845275,0.9958022,0.00009104555,0.0001500699,0.003102728],"study_design_scores_gemma":[0.000008840361,0.0002980313,0.001205775,0.000004234877,0.00003177794,0.0001987103,0.000008430955,0.001949603,0.9945134,0.00003425966,0.001735095,0.00001179702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6163264,0.004123511,0.3663508,0.0003650817,0.0001279531,0.0008167995,0.003200018,0.002551618,0.006137748],"genre_scores_gemma":[0.6321991,0.004522179,0.3346873,0.0002265728,0.00006520886,0.00129025,0.009227498,0.0003216612,0.01746034],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001718058,"threshold_uncertainty_score":0.006657183,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01266982224775237,"score_gpt":0.2302658826894695,"score_spread":0.2175960604417171,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}