{"id":"W4225378684","doi":"10.1096/fasebj.2022.36.s1.r3915","title":"The MCF Toxin of the Extracellular Pathogen <i>Vibrio vulnificus</i> is Activated by and Targets Host GTPases","year":2022,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Vibrio vulnificus; Microbiology; Virulence; Pathogen; Effector; Biology; Virulence factor; Toxin; Extracellular; Sepsis; Secretion; Bacteria; Immunology; Gene; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001236949,0.0004961164,0.0003065969,0.0002964603,0.0003665506,0.0005662747,0.0001589218,0.0006652894,0.002415081],"category_scores_gemma":[0.0001847705,0.0001373945,0.0004787801,0.0001642002,0.000270317,0.0002289171,0.0006919786,0.0005658818,0.001450915],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001022236,"about_ca_system_score_gemma":0.0003987618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002687469,"about_ca_topic_score_gemma":0.001319494,"domain_scores_codex":[0.9997502,0.00002609096,0.000008025402,0.00003648459,0.00009039813,0.00008879817],"domain_scores_gemma":[0.999917,0.000007255583,0.00002515451,0.000005020813,0.00001885373,0.00002668789],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001599241,0.00004291064,0.001664865,0.0001307601,0.00001237433,0.0002297451,0.0000558759,0.0002472103,0.9888476,0.001127711,0.001631616,0.005849304],"study_design_scores_gemma":[0.00007767816,0.0009825754,0.0718377,0.0001585547,0.00004391965,0.002293914,0.0004894937,0.004643802,0.8230476,0.001022638,0.09535826,0.00004366997],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9301795,0.01807754,0.006561809,0.001879634,0.0004741126,0.0001180511,0.002011118,0.0006639521,0.04003434],"genre_scores_gemma":[0.9786074,0.003415481,0.001644393,0.000625895,0.00006160414,0.00005041927,0.001916445,0.00003353584,0.01364491],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002687469,"threshold_uncertainty_score":0.00807929,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00824833604140281,"score_gpt":0.2260787014832716,"score_spread":0.2178303654418688,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}