{"id":"W4225386842","doi":"10.1080/15592294.2022.2069386","title":"Epigenetic aberrations of gene expression in a rat model of hepatocellular carcinoma","year":2022,"lang":"en","type":"article","venue":"Epigenetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; National Institute of Food and Agriculture; National Cancer Institute; National Institutes of Health; Uniwersytet Łódzki; Walther Cancer Foundation; Purdue University; U.S. Department of Agriculture","keywords":"Biology; DNA methylation; Epigenome; Carcinogenesis; Epigenetics; Transcriptome; Cancer research; Wnt signaling pathway; Gene; Methylation; Molecular biology; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001148112,0.000333947,0.0002303977,0.0007203285,0.0001767106,0.000137877,0.0001091557,0.0001218076,0.002143783],"category_scores_gemma":[0.00007315035,0.0001651722,0.0002311533,0.000281901,0.000212237,0.0000955084,0.0001579338,0.0003792954,0.0002742062],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002656112,"about_ca_system_score_gemma":0.0002547874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001965507,"about_ca_topic_score_gemma":0.002821393,"domain_scores_codex":[0.9998999,0.00001774091,0.000005159705,0.00001704643,0.00002937135,0.00003088077],"domain_scores_gemma":[0.9999312,0.000006667786,0.00001591864,0.00001110305,0.000009709551,0.00002536454],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000351671,0.00005414245,0.001126211,0.00001919397,0.00001117588,0.00008407905,0.00001687969,0.00006254066,0.9965743,0.00008238458,0.00004330368,0.001574294],"study_design_scores_gemma":[0.00002446443,0.001095701,0.03336756,0.000004629262,0.00005945687,0.0005152443,0.00009214465,0.001119611,0.962114,0.00009443997,0.001501989,0.00001077064],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949831,0.0007378457,0.002619387,0.00006449137,0.00004398357,0.00002298809,0.0003284895,0.0001152739,0.001084443],"genre_scores_gemma":[0.9945931,0.0005391437,0.0007790046,0.00001672315,0.000006650482,0.00003512114,0.0003973329,0.00001229585,0.003620743],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002143783,"threshold_uncertainty_score":0.007171631,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02211621624514757,"score_gpt":0.2461439136197918,"score_spread":0.2240276973746443,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}