{"id":"W4225386846","doi":"10.1096/fasebj.2022.36.s1.0r437","title":"Assembly Principles of the Human R2TP Chaperone Complex Reveal the Presence of R2T and R2P Complexes","year":2022,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Chaperone (clinical); Chemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001322175,0.0002414857,0.0001445904,0.0002413485,0.0001350672,0.0002890313,0.0001715899,0.0002816326,0.0004826558],"category_scores_gemma":[0.0001500962,0.0001627827,0.0002126443,0.0001456302,0.0001897407,0.0001783395,0.0001318707,0.0002433075,0.0003014728],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002628002,"about_ca_system_score_gemma":0.0001309149,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00057448,"about_ca_topic_score_gemma":0.0006028216,"domain_scores_codex":[0.9999208,0.00001072349,0.000008099113,0.0000290124,0.00001694575,0.00001443793],"domain_scores_gemma":[0.9999254,0.00001297565,0.00001603893,0.00001113568,0.000009131366,0.00002528983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000118314,0.00001724498,0.00226962,0.00004169957,0.00001339569,0.0003070243,0.00006751328,0.0006441281,0.9943849,0.0006609923,0.0001224664,0.001352782],"study_design_scores_gemma":[0.0000597637,0.0005073785,0.07121813,0.00002193076,0.00007530297,0.003717086,0.000225864,0.03069938,0.8783919,0.003351027,0.01167768,0.00005453933],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985615,0.001650521,0.01063686,0.0002020927,0.00001035754,0.00002737241,0.0002883721,0.0001397756,0.001429631],"genre_scores_gemma":[0.991239,0.0003141684,0.006250369,0.00008760934,0.00001024313,0.00002008155,0.0009822301,0.00002346336,0.001072712],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00057448,"threshold_uncertainty_score":0.001906753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05200889754310807,"score_gpt":0.3104005470240053,"score_spread":0.2583916494808973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}