{"id":"W4225388267","doi":"10.1096/fasebj.2022.36.s1.0r577","title":"Characterization of Protein Tyrosine Phosphatase 1B activator peptides in cells","year":2022,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Heart Institute","funders":"National Institutes of Health; American Heart Association","keywords":"Protein tyrosine phosphatase; Phosphorylation; Phosphatase; Dephosphorylation; Serine; Activator (genetics); Biochemistry; Tyrosine; Peptide sequence; Chemistry; Peptide; Cell biology; Effector; Tyrosine phosphorylation; Biology; Receptor; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001564046,0.0002419517,0.0001319763,0.0001259824,0.0001066213,0.0002386414,0.0001826746,0.0001871164,0.001002083],"category_scores_gemma":[0.0001778536,0.0001054109,0.0001584924,0.000167234,0.000107478,0.0001255217,0.0001137047,0.0004582771,0.0006368231],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00012796,"about_ca_system_score_gemma":0.0001623674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003156252,"about_ca_topic_score_gemma":0.000306225,"domain_scores_codex":[0.9998692,0.00001864864,0.000008193973,0.00002555071,0.00005281859,0.00002549011],"domain_scores_gemma":[0.9998848,0.00003028776,0.00002053113,0.00001273018,0.00002771294,0.00002401202],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002496801,0.00001395528,0.00005219577,0.00001016136,9.74251e-7,0.00001821075,0.000007815112,0.0000635476,0.9992286,0.0000390664,0.00001455783,0.0005259413],"study_design_scores_gemma":[0.00001390133,0.0002655948,0.00127915,0.000004334639,0.000008043616,0.0001101651,0.00001856484,0.000749235,0.9929971,0.00003630156,0.004514856,0.00000281017],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9798638,0.001612074,0.01382222,0.0001613134,0.00005510818,0.000172831,0.001071411,0.00005638588,0.0031849],"genre_scores_gemma":[0.9739143,0.001609275,0.01525976,0.0001677336,0.00002608926,0.0001809091,0.003903019,0.00005538879,0.004883513],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001002083,"threshold_uncertainty_score":0.003352284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008470863698385794,"score_gpt":0.2192102779913291,"score_spread":0.2107394142929433,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}