{"id":"W4225394234","doi":"10.1096/fasebj.2022.36.s1.r5343","title":"Intracellular Superoxide Radical Formation Decreases 6‐Mercaptopurine Uptake by MOLT‐4 Leukemia Cells","year":2022,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Oxidative stress; Chemistry; Superoxide dismutase; Pharmacology; Leukemia; Menadione; Cancer cell; Intracellular; Biochemistry; Oxidative phosphorylation; Cancer; Biology; Immunology; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001907064,0.000398736,0.0003954947,0.0002174045,0.0001779276,0.0003235688,0.0002831309,0.0003921048,0.002147044],"category_scores_gemma":[0.0001630197,0.0001255628,0.0003287481,0.0002688222,0.0001503003,0.0002714006,0.0001844492,0.0007346142,0.0004323138],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002785069,"about_ca_system_score_gemma":0.0001740791,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007663855,"about_ca_topic_score_gemma":0.0006956675,"domain_scores_codex":[0.9997426,0.00005475524,0.00002534728,0.00004726508,0.00006793506,0.00006207115],"domain_scores_gemma":[0.9998583,0.00003082364,0.00003834228,0.00001623274,0.0000355812,0.00002065017],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000417454,0.0001287571,0.0004268257,0.00009844527,0.00001463237,0.0000629941,0.00005693333,0.00008388585,0.9962587,0.00006781917,0.0001695692,0.002213951],"study_design_scores_gemma":[0.00003847293,0.0008131235,0.003094017,0.000007504093,0.00002329435,0.0001150723,0.00003585254,0.0006918741,0.9930485,0.00003530646,0.002092831,0.000004057412],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900365,0.003875262,0.002942548,0.0003366629,0.0001321075,0.00003858046,0.0007156017,0.0001916847,0.001731034],"genre_scores_gemma":[0.9929146,0.001143561,0.002116503,0.00009438688,0.00002864151,0.00006112002,0.0008802612,0.00001747163,0.002743455],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002147044,"threshold_uncertainty_score":0.007182598,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01377318839925338,"score_gpt":0.2463647605563396,"score_spread":0.2325915721570863,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}