{"id":"W4225399126","doi":"10.1096/fasebj.2022.36.s1.r5208","title":"Chemotherapy Drugs Induce Cachexia and Alter Muscle Protein Metabolism","year":2022,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Nutrition and Health in Aging","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brampton Civic Hospital; York University","funders":"","keywords":"Cachexia; Wasting; Medicine; Chemotherapy; Internal medicine; Weight loss; Gastrocnemius muscle; Regimen; Endocrinology; Cancer; Gastroenterology; Skeletal muscle; Obesity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000101126,0.0003266799,0.0002853452,0.0002735078,0.0001626255,0.0002035145,0.0001238538,0.0003140123,0.001935186],"category_scores_gemma":[0.00005853854,0.0001321919,0.0003111814,0.0001806253,0.0001860657,0.0002103435,0.0001784832,0.0004754845,0.0003731073],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003000045,"about_ca_system_score_gemma":0.000150856,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005324683,"about_ca_topic_score_gemma":0.001256628,"domain_scores_codex":[0.9998972,0.00001038876,0.000008966563,0.00002143817,0.00003321518,0.00002871222],"domain_scores_gemma":[0.9999377,0.000004710628,0.00002504673,0.00000515808,0.000007581423,0.00001984459],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004450274,0.0001020735,0.001070966,0.0001051435,0.000021106,0.00008391366,0.00001811407,0.00005472028,0.9939911,0.0001231069,0.0002444666,0.003740226],"study_design_scores_gemma":[0.0002723739,0.007338633,0.11788,0.00008616979,0.0001019628,0.001906982,0.0001235647,0.0009642937,0.8530604,0.0002027559,0.01804136,0.00002150187],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838483,0.01021137,0.001173756,0.0001793062,0.00007752742,0.00008829912,0.00119036,0.00009400989,0.003137076],"genre_scores_gemma":[0.9851444,0.006032081,0.001250619,0.0002545628,0.0000178754,0.0001492071,0.00135763,0.00001613674,0.005777529],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001935186,"threshold_uncertainty_score":0.006473839,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02813710095477385,"score_gpt":0.3003540329545173,"score_spread":0.2722169319997435,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}