{"id":"W4225418877","doi":"10.1096/fasebj.2022.36.s1.r2313","title":"Scleraxis is Required for Induction of GLS1 Expression in Cardiac Myofibroblasts","year":2022,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Medical Imaging and Pathology Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Boniface Hospital","funders":"Canadian Institutes of Health Research","keywords":"Cardiac fibrosis; Myofibroblast; Glutaminolysis; Transactivation; Cell biology; Glutaminase; Cancer research; Transcription factor; Biology; Gene knockdown; Fibrosis; Chemistry; Molecular biology; Glutamine; Pathology; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001050013,0.00006103004,0.0002198477,0.00008906392,0.0002552946,0.000003674544,0.00007428179,0.00002557147,0.0001189497],"category_scores_gemma":[0.0001686912,0.00003866816,0.000101453,0.0001233831,0.0001038511,0.00003289338,0.00005976641,0.0003776601,0.000001555572],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004740284,"about_ca_system_score_gemma":0.00006032582,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006919881,"about_ca_topic_score_gemma":2.671105e-7,"domain_scores_codex":[0.9991104,0.0001779479,0.0002303982,0.00008850567,0.0002450671,0.0001476714],"domain_scores_gemma":[0.9995456,0.0001080584,0.0001172198,0.0001244711,0.00005215062,0.00005250381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007245302,0.0001281719,0.02407152,0.00005856821,0.0000847491,0.00003104527,0.006902954,0.00004252734,0.9126204,0.0000158888,0.04114138,0.01417833],"study_design_scores_gemma":[0.0103526,0.003133105,0.1151503,0.001173327,0.0004426821,0.002086358,0.02154851,0.0006659379,0.8196755,0.003311361,0.02208686,0.0003734436],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917517,0.001006489,0.0003645146,0.005761873,0.0006145248,0.0001754648,0.00001714937,0.000007784994,0.0003005333],"genre_scores_gemma":[0.9980681,0.0001047821,0.0005674516,0.0004622748,0.0002582826,0.00002433474,0.000004262843,0.000007912516,0.0005026179],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09294482,"threshold_uncertainty_score":0.1963545,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04853085745786088,"score_gpt":0.3088547303738393,"score_spread":0.2603238729159784,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}