{"id":"W4225418877","doi":"10.1096/fasebj.2022.36.s1.r2313","title":"Scleraxis is Required for Induction of GLS1 Expression in Cardiac Myofibroblasts","year":2022,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Medical Imaging and Pathology Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Boniface Hospital","funders":"Canadian Institutes of Health Research","keywords":"Cardiac fibrosis; Myofibroblast; Glutaminolysis; Transactivation; Cell biology; Glutaminase; Cancer research; Transcription factor; Biology; Gene knockdown; Fibrosis; Chemistry; Molecular biology; Glutamine; Pathology; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001625219,0.0004223786,0.0002771082,0.000389926,0.0002090855,0.0003257559,0.0001650735,0.0003408949,0.002585101],"category_scores_gemma":[0.0001320925,0.0002113795,0.0004385085,0.0001879277,0.0003209521,0.0001814458,0.0003311233,0.0007269778,0.001006762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003460523,"about_ca_system_score_gemma":0.0002474475,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000922616,"about_ca_topic_score_gemma":0.00165566,"domain_scores_codex":[0.9996723,0.00003918571,0.00003455657,0.00006636137,0.0001253842,0.00006229022],"domain_scores_gemma":[0.9997082,0.00003639327,0.0001040873,0.00002368148,0.00002789744,0.00009978173],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000417624,0.00000718835,0.0001107274,0.00001787931,0.000001538645,0.00003836356,0.000008162739,0.000009320798,0.9994453,0.00002137594,0.00003700491,0.0002613396],"study_design_scores_gemma":[0.00001925625,0.0001344643,0.01745275,0.00001126448,0.000009578874,0.0004110145,0.0000524653,0.0005937639,0.9780727,0.00003579495,0.00320051,0.000006413606],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880923,0.001937094,0.004425495,0.0003175726,0.00007170632,0.00004804915,0.00239144,0.000278733,0.002437582],"genre_scores_gemma":[0.9864635,0.0006963381,0.003088155,0.0001990301,0.00001669808,0.00007515826,0.003215321,0.0000732257,0.006172483],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002585101,"threshold_uncertainty_score":0.008648038,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04853085745786088,"score_gpt":0.3088547303738393,"score_spread":0.2603238729159784,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}