{"id":"W4225514393","doi":"10.1177/1759720x221084848","title":"Infigratinib in children with achondroplasia: the PROPEL and PROPEL 2 studies","year":2022,"lang":"en","type":"article","venue":"Therapeutic Advances in Musculoskeletal Disease","topic":"Connective tissue disorders research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Stollery Children's Hospital; University of Alberta","funders":"","keywords":"MEDLINE; Disease; Context (archaeology); Field (mathematics)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002650888,0.0005357132,0.001013826,0.0003636206,0.0002122882,0.0006518557,0.0004444662,0.0007568225,0.002280443],"category_scores_gemma":[0.00281664,0.0001801789,0.001928004,0.0007703699,0.0004514816,0.0006211828,0.0004553786,0.001384972,0.0002482308],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001050326,"about_ca_system_score_gemma":0.001694376,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001956264,"about_ca_topic_score_gemma":0.005748867,"domain_scores_codex":[0.9987729,0.0005282193,0.0001572483,0.0001633241,0.0002651695,0.0001131192],"domain_scores_gemma":[0.9974056,0.0009577553,0.0009296517,0.0001037318,0.0002195291,0.000383689],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1235323,0.003321193,0.1556178,0.01404408,0.01521042,0.00190279,0.000707255,0.0015563,0.008179533,0.002166604,0.01674771,0.6570141],"study_design_scores_gemma":[0.1587348,0.1442363,0.459039,0.006901809,0.02394984,0.01153014,0.0008728596,0.001207033,0.008812883,0.001382042,0.1831669,0.0001664405],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.58316,0.3912941,0.0007151115,0.004952739,0.0003487408,0.001474598,0.005137193,0.00004935422,0.01286818],"genre_scores_gemma":[0.889798,0.09901547,0.002263345,0.002868474,0.0003701584,0.001011868,0.00316098,0.00001568507,0.001496079],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002650888,"threshold_uncertainty_score":0.01401937,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01122402977626885,"score_gpt":0.3195150959348841,"score_spread":0.3082910661586152,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}