{"id":"W4225552440","doi":"","title":"MSR1 and NEP Are Correlated with Alzheimer’s Disease Amyloid Pathology and Apolipoprotein Alterations","year":2022,"lang":"en","type":"article","venue":"eScholarship@McGill (McGill)","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Douglas College","funders":"","keywords":"Apolipoprotein E; Cerebrospinal fluid; Pathology; Neprilysin; Amyloid (mycology); Alzheimer's disease; Internal medicine; Endocrinology; Medicine; Chemistry; Disease; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003151646,0.0004599583,0.0004040088,0.0006924546,0.000184468,0.0004744362,0.000176524,0.0003704398,0.001257809],"category_scores_gemma":[0.0003098903,0.0002867485,0.0003509115,0.0003243477,0.0002207551,0.0001716202,0.0002496613,0.0005902748,0.0004618369],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001458915,"about_ca_system_score_gemma":0.00008937968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003363574,"about_ca_topic_score_gemma":0.0006098764,"domain_scores_codex":[0.9996563,0.00003182885,0.00002528081,0.0001437173,0.0001025062,0.00004038383],"domain_scores_gemma":[0.9994354,0.00004090766,0.0003499764,0.00004766036,0.00005885987,0.00006728653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001194834,0.00007686203,0.04498655,0.00009611915,0.0001271828,0.0004614216,0.0001346428,0.0001456007,0.9462257,0.00009427613,0.0002077671,0.006249009],"study_design_scores_gemma":[0.00002735219,0.0003085623,0.8595436,0.00002001026,0.0001373023,0.003173335,0.0001666395,0.001270879,0.1330341,0.0002697436,0.002023813,0.00002478289],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997053,0.0008350479,0.001108023,0.00004174847,0.000008738061,0.0000043752,0.0005129961,0.00004971014,0.000386263],"genre_scores_gemma":[0.9954076,0.0003324036,0.001696024,0.00006636942,0.00001230998,0.00002418778,0.0008240217,0.00003765909,0.001599293],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001257809,"threshold_uncertainty_score":0.00420779,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02358627669884966,"score_gpt":0.260666132869794,"score_spread":0.2370798561709443,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}