{"id":"W4225577530","doi":"10.3390/cells11060966","title":"Chromatin Reorganization during Myoblast Differentiation Involves the Caspase-Dependent Removal of SATB2","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research; Ottawa Hospital Research Institute","keywords":"Chromatin; Cell biology; Chromatin remodeling; Scaffold/matrix attachment region; Derepression; Biology; Cellular differentiation; Gene; Genetics; Gene expression; Psychological repression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000107437,0.00008031348,0.00007562196,0.0000220489,0.0001803539,0.00001372577,0.0001811353,0.00003586064,0.00007995835],"category_scores_gemma":[0.00001226091,0.00007112788,0.00004332755,0.00007189584,0.00002904388,0.000001611734,0.0002392394,0.00006306414,0.000003211444],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003358517,"about_ca_system_score_gemma":0.00003165091,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001543317,"about_ca_topic_score_gemma":0.00002394644,"domain_scores_codex":[0.9993606,0.00006424644,0.000177596,0.0001592838,0.0001322056,0.0001061238],"domain_scores_gemma":[0.999526,0.000006286156,0.0001436149,0.0002682723,0.00003558019,0.0000203111],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001256584,0.00003880506,0.0003013313,0.00002317162,0.00002016786,0.000002412261,0.0002013417,0.002515897,0.9965525,0.00006356605,0.0001647801,0.0001034925],"study_design_scores_gemma":[0.0003239202,0.00008709304,0.007023762,0.000004016739,0.0000178543,0.00004255051,0.0005202608,0.001391127,0.9897637,0.00008109641,0.0006338591,0.0001107732],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987813,0.0001760959,0.0003863391,0.00005994577,0.000175142,0.0001307136,0.00003624105,0.000007091429,0.0002471465],"genre_scores_gemma":[0.9986712,0.00005782225,0.0001832373,0.0000375235,0.00007402069,0.000009812563,0.0001582882,0.00002028454,0.0007877963],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006788781,"threshold_uncertainty_score":0.290051,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003464939759079765,"score_gpt":0.1730788079823068,"score_spread":0.169613868223227,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}