{"id":"W4225658865","doi":"10.1128/aac.02406-21","title":"Differential Response of <i>Candida</i> Species Morphologies and Isolates to Fluconazole and Boric Acid","year":2022,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada; University of Manitoba","keywords":"Fluconazole; Candida albicans; Corpus albicans; Microbiology; Biology; Boric acid; Azole; Biofilm; Population; Yeast; Drug resistance; Antifungal drug; Candida glabrata; Bacteria; Chemistry; Antifungal; Medicine; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003507707,0.0002960192,0.0004519208,0.0006165063,0.0002032242,0.000540945,0.0002011785,0.0003935776,0.001030848],"category_scores_gemma":[0.001018268,0.000147281,0.0002893572,0.0004538476,0.0002004713,0.0002693841,0.0004760085,0.0003438606,0.0002500494],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001549858,"about_ca_system_score_gemma":0.0001347363,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001689892,"about_ca_topic_score_gemma":0.001861071,"domain_scores_codex":[0.9991033,0.0001666329,0.0001206222,0.0002082906,0.0002310184,0.0001700826],"domain_scores_gemma":[0.9994066,0.0001274053,0.0001379365,0.00006748535,0.0001839661,0.00007660223],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000427566,0.00008330119,0.04051529,0.00008671666,0.0000500532,0.0001852877,0.0001503405,0.00008413711,0.9481442,0.0000424266,0.0001690506,0.01006156],"study_design_scores_gemma":[0.00002231119,0.001759495,0.6470122,0.00004785313,0.0000956354,0.003086556,0.0007252372,0.0007259641,0.3424736,0.0001429564,0.003869358,0.00003886997],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963123,0.0009641667,0.0007112181,0.00008422144,0.00001819447,0.00003696836,0.0003989078,0.0000270186,0.001446989],"genre_scores_gemma":[0.9970794,0.0004603093,0.001027705,0.0001669832,0.00001252075,0.00002250786,0.000701657,0.0000155296,0.0005135089],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001689892,"threshold_uncertainty_score":0.003448606,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0121317645982816,"score_gpt":0.2494888239564671,"score_spread":0.2373570593581855,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}