{"id":"W4225660631","doi":"10.1080/19490976.2022.2052699","title":"The barrier and beyond: Roles of intestinal mucus and mucin-type O-glycosylation in resistance and tolerance defense strategies guiding host-microbe symbiosis","year":2022,"lang":"en","type":"review","venue":"Gut Microbes","topic":"Probiotics and Fermented Foods","field":"Agricultural and Biological Sciences","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"Okanagan University College; University of British Columbia, Okanagan Campus; University of British Columbia","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; National Institutes of Health; Crohn's and Colitis Canada","keywords":"Biology; Mucus; Mucin; Microbiology; Gut flora; Host (biology); Microbiome; Symbiosis; Colonisation resistance; Immunology; Bacteria; Ecology; Bioinformatics; Biochemistry; Genetics; Antibiotics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004489126,0.0007368547,0.001007016,0.00165505,0.0002304261,0.001104355,0.0006415157,0.001118706,0.002310164],"category_scores_gemma":[0.0005634495,0.0001785573,0.0003912862,0.001638782,0.0004366968,0.001486067,0.0007370941,0.001627717,0.001031807],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004377709,"about_ca_system_score_gemma":0.001007121,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000809845,"about_ca_topic_score_gemma":0.001271561,"domain_scores_codex":[0.9998626,0.0000225053,0.00001997673,0.00002220881,0.00005477362,0.00001781621],"domain_scores_gemma":[0.9997848,0.00009533007,0.00003269006,0.000005095326,0.00005389469,0.00002834236],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009051121,0.00005778625,0.0002580033,0.01967281,0.0001021677,0.0002590361,0.00009836384,0.0002641648,0.003114241,0.005627403,0.02366831,0.9467872],"study_design_scores_gemma":[0.00001101836,0.0001097335,0.001243693,0.003916075,0.00009475543,0.00125214,0.0001018084,0.00007872352,0.0004840592,0.001842218,0.9908481,0.00001767168],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009840089,0.9989523,0.00007186541,0.0002231191,0.0001676124,0.000001942027,0.000008016083,0.000003089394,0.0004736524],"genre_scores_gemma":[0.0004481254,0.9989133,0.00009118752,0.0001157981,0.0001148286,0.000002402219,0.00001290147,6.506495e-7,0.0003007867],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002310164,"threshold_uncertainty_score":0.007728219,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03001053240914991,"score_gpt":0.2505811241654466,"score_spread":0.2205705917562967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}