{"id":"W4225660631","doi":"10.1080/19490976.2022.2052699","title":"The barrier and beyond: Roles of intestinal mucus and mucin-type O-glycosylation in resistance and tolerance defense strategies guiding host-microbe symbiosis","year":2022,"lang":"en","type":"review","venue":"Gut Microbes","topic":"Probiotics and Fermented Foods","field":"Agricultural and Biological Sciences","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"Okanagan University College; University of British Columbia, Okanagan Campus; University of British Columbia","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; National Institutes of Health; Crohn's and Colitis Canada","keywords":"Biology; Mucus; Mucin; Microbiology; Gut flora; Host (biology); Microbiome; Symbiosis; Colonisation resistance; Immunology; Bacteria; Ecology; Bioinformatics; Biochemistry; Genetics; Antibiotics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003722971,0.0002507439,0.0005225175,0.00003172985,0.0003220151,0.0001573545,0.000189579,0.0001222958,0.00002066344],"category_scores_gemma":[0.000067461,0.0001014397,0.0000641816,0.0002814484,0.0001941891,0.00009084778,0.0002023453,0.0001916377,4.320228e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002737008,"about_ca_system_score_gemma":0.00002817562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006099084,"about_ca_topic_score_gemma":0.001281281,"domain_scores_codex":[0.9987316,0.0001471838,0.0004239298,0.0003764599,0.00008901964,0.0002317979],"domain_scores_gemma":[0.9991763,0.0004150862,0.0002448874,0.00007614852,0.00004053851,0.00004704609],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009529945,0.00006865237,0.0009057822,0.002743288,0.00008435637,0.00001405846,0.0006902299,6.68567e-7,0.104677,0.002140759,0.0002071029,0.8883728],"study_design_scores_gemma":[0.0001705092,0.0002878845,0.002483078,0.003380454,0.0001558586,0.00008069962,0.001298328,0.000009187322,0.0002398105,0.000731396,0.9906626,0.0005001688],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1039951,0.8952518,5.361464e-7,0.00008627256,0.00006021544,0.0002945512,0.00007894767,0.00001180644,0.0002208124],"genre_scores_gemma":[0.04336072,0.9563391,0.00009773099,0.00002551775,0.00003119343,0.00001163055,0.00005409395,0.000002989943,0.00007702878],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9904555,"threshold_uncertainty_score":0.4136591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03001053240914991,"score_gpt":0.2505811241654466,"score_spread":0.2205705917562967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}