{"id":"W4225667275","doi":"10.26686/wgtn.17008537.v1","title":"Tobacco smoke extract modulates activity and expression of monoamine oxidase and μ opioid receptor in cultured human neuroblastoma cells","year":2010,"lang":"en","type":"dissertation","venue":"","topic":"Nicotinic Acetylcholine Receptors Study","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Wellington Medical Research Foundation","keywords":"Nicotine; Addiction; Monoamine oxidase; Tobacco smoke; Pharmacology; Opioid receptor; Opioid; Monoamine oxidase A; Chemistry; Receptor; Medicine; Enzyme; Biochemistry; Internal medicine; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009724523,0.000191364,0.0002111098,0.0001827135,0.0001084289,0.000181346,0.0001100227,0.0001611031,0.0009472161],"category_scores_gemma":[0.00009196188,0.0001171052,0.0002946502,0.0001839509,0.0001025823,0.0001104571,0.0001225772,0.0003155052,0.000295243],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001639983,"about_ca_system_score_gemma":0.0001684175,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003566164,"about_ca_topic_score_gemma":0.007221617,"domain_scores_codex":[0.9998919,0.00001158506,0.00001528026,0.00002375078,0.00003426429,0.00002334203],"domain_scores_gemma":[0.999945,0.00001472209,0.000009993285,0.000005874407,0.00001471527,0.000009699476],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001069945,0.00003515928,0.0006469818,0.00003034129,0.000008306508,0.00003770356,0.00003932327,0.00001626313,0.9980468,0.00001463047,0.00002725303,0.0009903795],"study_design_scores_gemma":[0.00001451251,0.001134188,0.04568984,0.00001464594,0.00005359587,0.0002698271,0.0001885668,0.0005280477,0.9498118,0.0000239659,0.002262734,0.000008279117],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944904,0.002974697,0.0005776346,0.00004993815,0.00003068068,0.00001223341,0.000499584,0.00001749517,0.00134731],"genre_scores_gemma":[0.9863313,0.003275906,0.001444982,0.00006953088,0.00001214075,0.0000377116,0.001779498,0.0000102445,0.007038629],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003566164,"threshold_uncertainty_score":0.007090807,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007104449955794709,"score_gpt":0.2671410269999244,"score_spread":0.2600365770441297,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}