{"id":"W4225674000","doi":"10.3390/biomedinformatics1030013","title":"Gibbs Free Energy, a Thermodynamic Measure of Protein–Protein Interactions, Correlates with Neurologic Disability","year":2021,"lang":"en","type":"article","venue":"BioMedInformatics","topic":"Bioinformatics and Genomic Networks","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Gibbs free energy; Neuropathology; Disease; Correlation; Multiple sclerosis; Psychology; Neuroscience; Medicine; Psychiatry; Thermodynamics; Physics; Internal medicine; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001875237,0.0002102253,0.0002307017,0.00003450373,0.0000768019,0.00003470769,0.0003122388,0.0001827462,0.0000373761],"category_scores_gemma":[0.00008279869,0.0001610048,0.0001046438,0.0002042862,0.0002701645,0.00001892743,0.0002490182,0.0001560321,0.000004600322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000226057,"about_ca_system_score_gemma":0.0001438799,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001393377,"about_ca_topic_score_gemma":0.00008170352,"domain_scores_codex":[0.9987883,0.00004146361,0.0005190715,0.000169046,0.0002192638,0.0002628299],"domain_scores_gemma":[0.9986604,0.00001546657,0.0003002041,0.0007375767,0.0001923415,0.00009404102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001304922,0.001230099,0.004287857,0.001517015,0.0009659443,0.00002340454,0.001355334,0.000666281,0.8731778,0.01047581,0.004541275,0.1004543],"study_design_scores_gemma":[0.01199127,0.006903662,0.007247981,0.001170999,0.0005510428,0.001004299,0.005007318,0.126414,0.6441535,0.02045307,0.1709556,0.004147322],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.963956,0.0004741164,0.03014026,0.000399521,0.0001992469,0.0003853248,0.0001191944,0.00002997106,0.004296367],"genre_scores_gemma":[0.9951442,0.00003122047,0.00388658,0.000166581,0.00008159951,0.00004508196,0.0002814284,0.00001765728,0.0003456191],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2290243,"threshold_uncertainty_score":0.6565586,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006243973989118277,"score_gpt":0.1996391558080114,"score_spread":0.1933951818188932,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}