{"id":"W4225723737","doi":"10.1093/oncolo/oyac092","title":"Longitudinal Changes in Skeletal Muscle Metabolism, Oxygen Uptake, and Myosteatosis During Cardiotoxic Treatment for Early-Stage Breast Cancer","year":2022,"lang":"en","type":"article","venue":"The Oncologist","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of Toronto","funders":"Canadian Institutes of Health Research; University Hospital Foundation; Heart and Stroke Foundation of Canada","keywords":"Medicine; Breast cancer; Skeletal muscle; Chemotherapy; Internal medicine; VO2 max; Cancer; Cardiology; Blood pressure; Heart rate","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003220208,0.000139633,0.0002501646,0.0001777955,0.000170776,0.0002168449,0.0001200802,0.000229753,0.0005612361],"category_scores_gemma":[0.0005799513,0.00009465485,0.0001557814,0.0001900118,0.00009597567,0.0001417299,0.0001737564,0.0003239663,0.0001372293],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002188908,"about_ca_system_score_gemma":0.0001291998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000844304,"about_ca_topic_score_gemma":0.001671169,"domain_scores_codex":[0.9999151,0.00002044829,0.00000649713,0.00001740723,0.00001848711,0.00002193344],"domain_scores_gemma":[0.9995255,0.00006532537,0.0002209906,0.00002438967,0.00006030712,0.0001033735],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003096252,0.000332873,0.9673874,0.0000253117,0.00005867847,0.0001960205,0.000140126,0.0002682204,0.01796486,0.00000785345,0.00008815017,0.01043429],"study_design_scores_gemma":[0.00001495097,0.001176448,0.9968063,0.000002828638,0.00002542254,0.0002195362,0.00004212306,0.0001464608,0.001429869,0.000007527046,0.0001256922,0.000002961579],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996943,0.0001121409,0.00004790418,0.00000846281,6.602743e-7,0.000005194683,0.00005079541,0.000001670175,0.00007879084],"genre_scores_gemma":[0.9994926,0.00006088004,0.00006192298,0.00001372553,0.00000180599,0.000009983249,0.0002095723,7.348565e-7,0.0001487383],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000844304,"threshold_uncertainty_score":0.001877546,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03960038994207725,"score_gpt":0.3045700424354185,"score_spread":0.2649696524933412,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}