{"id":"W4225758339","doi":"10.3389/fpsyt.2022.804168","title":"Sex Modulates the Pathological Aging Effect on Caudate Functional Connectivity in Mild Cognitive Impairment","year":2022,"lang":"en","type":"article","venue":"Frontiers in Psychiatry","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; National Institute of General Medical Sciences; H. Lundbeck A/S; Servier; Eisai; Northern California Institute for Research and Education; Pfizer; Biogen; BioClinica; Bristol-Myers Squibb; Cleveland Clinic; F. Hoffmann-La Roche; University of Southern California; Novartis Pharmaceuticals Corporation; U.S. Department of Defense; Eli Lilly and Company; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics; National Institute on Aging; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Caudate nucleus; Pathological; Psychology; Neuropsychology; Internal medicine; Cognition; Neuroimaging; Medicine; Neuroscience","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003531759,0.0002700661,0.0002667715,0.0003318764,0.0002256929,0.0002713411,0.0001900743,0.0002462906,0.001782045],"category_scores_gemma":[0.001457287,0.00009231719,0.0001640194,0.0001821871,0.0002359182,0.0002555597,0.0002215562,0.0001185217,0.0001030473],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001169338,"about_ca_system_score_gemma":0.000137969,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002409767,"about_ca_topic_score_gemma":0.005872926,"domain_scores_codex":[0.999887,0.00003181271,0.000008570509,0.00003459169,0.00002153492,0.00001649462],"domain_scores_gemma":[0.9996245,0.0000889947,0.0001588885,0.00004668339,0.0000391348,0.00004181848],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001911281,0.0001253504,0.9463878,0.00007076052,0.00027915,0.0006047276,0.0006653466,0.0001943603,0.02626143,0.0001306873,0.0002299806,0.02313903],"study_design_scores_gemma":[0.000004044478,0.0000775927,0.9992047,0.000003200071,0.00001751016,0.0001769598,0.00003996481,0.00009395587,0.0002730008,0.00005601652,0.00005135925,0.000001691814],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991425,0.0003640672,0.0001148604,0.00001805062,0.000003421052,0.000004245514,0.0001112061,0.000003545704,0.0002379858],"genre_scores_gemma":[0.9994804,0.00009282338,0.0001143815,0.00001565639,0.000005638843,0.000004073757,0.00009469686,0.000002472202,0.0001898714],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002409767,"threshold_uncertainty_score":0.005961478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01202957358233183,"score_gpt":0.284171076125625,"score_spread":0.2721415025432932,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}