{"id":"W4225815647","doi":"10.1080/19490976.2022.2035658","title":"Evaluating live microbiota biobanking using an <i>ex vivo</i> microbiome assay and metaproteomics","year":2022,"lang":"en","type":"article","venue":"Gut Microbes","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Economic Development and Innovation","keywords":"Biology; Microbiome; Metaproteomics; Prebiotic; Biobank; Feces; Fecal bacteriotherapy; Gut flora; Ex vivo; Glycerol; Microbiology; Metagenomics; In vivo; Food science; Biotechnology; Immunology; Bioinformatics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001466201,0.0003818071,0.0005732844,0.0004257732,0.0008600853,0.0001594705,0.000310304,0.0001295993,0.001206386],"category_scores_gemma":[0.0001278574,0.000393557,0.0001864338,0.0006317827,0.0002068451,0.000146962,0.000814135,0.0007435365,0.00003951673],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005080851,"about_ca_system_score_gemma":0.0004280595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007228642,"about_ca_topic_score_gemma":0.00002854307,"domain_scores_codex":[0.9969515,0.0003918572,0.0005392684,0.000854291,0.0004662288,0.0007968576],"domain_scores_gemma":[0.9986152,0.0001190572,0.0001817848,0.0006231813,0.000203004,0.000257787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002256524,0.0003943728,0.0006871833,0.0001377951,0.0001442241,0.00006742059,0.0008741572,0.0001390912,0.993496,0.00001095637,0.0006177267,0.003205412],"study_design_scores_gemma":[0.002565032,0.001030193,0.000227698,0.0001322533,0.0004210358,0.002248204,0.002231722,0.004623832,0.9763148,0.00003949401,0.009539567,0.0006261381],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949133,0.002883076,0.00007826899,0.0004228427,0.0002241076,0.0009390548,0.0002795428,0.0001021462,0.0001576632],"genre_scores_gemma":[0.9876524,0.0001416264,0.009940832,0.0006991005,0.0003226141,0.0000420214,0.0001919434,0.0001182641,0.000891261],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01718118,"threshold_uncertainty_score":0.9998516,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08740359754432715,"score_gpt":0.364784160925703,"score_spread":0.2773805633813759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}