{"id":"W4225835073","doi":"10.1177/11779322221085077","title":"Molnupiravir Does Not Induce Mutagenesis in Host Lung Cells during SARS-CoV-2 Treatment","year":2022,"lang":"en","type":"article","venue":"Bioinformatics and Biology Insights","topic":"Plant Virus Research Studies","field":"Agricultural and Biological Sciences","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Mutagenesis; Mutation; Host (biology); Biology; Virology; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Coronavirus disease 2019 (COVID-19); Genetics; Cell biology; Computational biology; Gene; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001228619,0.000176687,0.000386863,0.0001316128,0.0001923395,0.0003298825,0.0001671195,0.0003465246,0.002484985],"category_scores_gemma":[0.0002665244,0.0001103577,0.0002354418,0.00008867614,0.0001369022,0.0001849409,0.000160052,0.0005537305,0.0005641967],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001692543,"about_ca_system_score_gemma":0.0001758493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006485209,"about_ca_topic_score_gemma":0.0014854,"domain_scores_codex":[0.999823,0.00003348304,0.00001140199,0.00004700178,0.00004733199,0.00003776872],"domain_scores_gemma":[0.9998494,0.00004852758,0.00002186046,0.00002714275,0.00002795822,0.00002498696],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001665097,0.0000354425,0.0003571953,0.00004573645,0.000006199905,0.00004419818,0.00002361218,0.00006739352,0.997472,0.00002924499,0.000114668,0.001637845],"study_design_scores_gemma":[0.00001227901,0.0009196195,0.007221953,0.00001051953,0.00001563671,0.0001800822,0.00007461505,0.0008832372,0.9863458,0.00005101263,0.004277921,0.000007279945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907694,0.002717697,0.002361052,0.0001531893,0.0001038151,0.00008364081,0.0009897522,0.0001904258,0.002630963],"genre_scores_gemma":[0.9929894,0.0004801737,0.001584128,0.0001908882,0.00001444008,0.00006263433,0.001275072,0.00005219528,0.003351024],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002484985,"threshold_uncertainty_score":0.00831306,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05590959123686111,"score_gpt":0.2752611054188153,"score_spread":0.2193515141819542,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}