{"id":"W4225927876","doi":"10.21203/rs.3.rs-1194469/v2","title":"Analysis of Rhodopsin G Protein-Coupled Receptor Orthologs Reveals Semiochemical Peptides for Parasite (Schistosoma Mansoni) and Host (Biomphalaria Glabrata) Interplay","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Neuroendocrine regulation and behavior","field":"Psychology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Francis Xavier University","funders":"National Institute of Allergy and Infectious Diseases; National Health and Medical Research Council; Australian Research Council; Medical Research Council; National Cancer Institute; National Institutes of Health; Australian Government; University of the Sunshine Coast; QIMR Berghofer Medical Research Institute; National Computational Infrastructure","keywords":"Biomphalaria glabrata; Biology; Schistosoma mansoni; Snail; G protein-coupled receptor; Schistosoma; Intermediate host; Rhodopsin; Obligate; Receptor; Genetics; Host (biology); Ecology; Zoology; Schistosomiasis; Helminths; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008863852,0.0001399479,0.0001502631,0.0004115345,0.000134995,0.000147384,0.0001092094,0.0001924129,0.000995468],"category_scores_gemma":[0.0001783956,0.00006383919,0.0002597351,0.0002446917,0.0001075027,0.00008070601,0.0001889163,0.000163345,0.0002585077],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001199179,"about_ca_system_score_gemma":0.0001019222,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006785529,"about_ca_topic_score_gemma":0.000998255,"domain_scores_codex":[0.999945,0.000007095294,0.000004314452,0.00001870881,0.00001188286,0.00001297693],"domain_scores_gemma":[0.9998771,0.00002108975,0.00005734007,0.00000694699,0.00001158693,0.00002592775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001754603,0.00002554677,0.008806809,0.00004738677,0.00001207815,0.0002019287,0.00004591788,0.00006129387,0.9893523,0.00003558286,0.00002862986,0.001207113],"study_design_scores_gemma":[0.00002771498,0.0006216909,0.9122109,0.00001447636,0.00006258929,0.002137145,0.0004082502,0.00254703,0.08012123,0.00009268005,0.001745493,0.00001077283],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989253,0.00007890001,0.0003683064,0.00001594381,0.000001402387,0.0000084563,0.0003853727,0.00001584481,0.0002004167],"genre_scores_gemma":[0.997138,0.00005821347,0.001151693,0.00002851336,0.000001351976,0.0000123197,0.001325042,0.00000515654,0.000279691],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000995468,"threshold_uncertainty_score":0.003330112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07235041874890384,"score_gpt":0.4562121746413594,"score_spread":0.3838617558924555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}