{"id":"W4226002495","doi":"10.1093/biolre/ioac066","title":"Paternal obesity induces placental hypoxia and sex-specific impairments in placental vascularization and offspring metabolism","year":2022,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Birth, Development, and Health","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; Population Health Research Institute; McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; National Health Research Institutes; Conselho Nacional de Desenvolvimento Científico e Tecnológico; McMaster University","keywords":"Offspring; Biology; Endocrinology; Internal medicine; Placenta; Fetus; Hypoxia (environmental); Pregnancy; Angiogenesis; Gestation; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005862511,0.00008655528,0.000216023,0.0001507902,0.0001290124,0.000003551428,0.00002828941,0.00006048542,0.00002527463],"category_scores_gemma":[0.00001581963,0.00008402133,0.00001905055,0.0001097091,0.00008035372,0.00005953871,0.00008717099,0.0001802329,5.773888e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008534167,"about_ca_system_score_gemma":0.00004727236,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002025049,"about_ca_topic_score_gemma":0.000009635948,"domain_scores_codex":[0.9990078,0.0001113068,0.0002288294,0.0004054118,0.0001041526,0.0001424825],"domain_scores_gemma":[0.9996921,0.000007012724,0.0001073607,0.0001297849,0.0000178496,0.00004583445],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000217893,0.0002120779,0.9116478,0.00006299824,0.00003520488,0.000005539605,0.001176334,0.000002244622,0.06909983,0.000550482,0.00002215861,0.01696741],"study_design_scores_gemma":[0.001477003,0.0002055829,0.9831064,0.0000127912,0.00001226369,0.0003170466,0.0007251261,0.0000198918,0.0121482,0.0005501327,0.001349716,0.00007587931],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951899,0.003711992,0.00002543055,0.0002331632,0.0004540381,0.0003184864,0.00000654468,0.00001939865,0.00004106283],"genre_scores_gemma":[0.9873477,0.01189901,0.0005103959,0.00002932745,0.0001149642,0.00001369334,0.00005718935,0.000007024904,0.00002072807],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07145855,"threshold_uncertainty_score":0.342629,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02046458319025508,"score_gpt":0.258871432898595,"score_spread":0.23840684970834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}