{"id":"W4226032294","doi":"10.5114/fn.2022.113561","title":"microRNA-146a as a biomarker for transmissible spongiform encephalopathy","year":2022,"lang":"en","type":"article","venue":"Folia Neuropathologica","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Research Resources; National Institute of Neurological Disorders and Stroke; National Eye Institute; University of Toronto; Louisiana Biomedical Research Network; National Institutes of Health; Louisiana State University; National Institute on Aging; Research to Prevent Blindness","keywords":"Biomarker; Transmissible spongiform encephalopathy; microRNA; Virology; Encephalopathy; Biology; Medicine; Pathology; Gene; Internal medicine; Genetics; Prion protein; Scrapie; Disease","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001075006,0.0003494826,0.0004883031,0.001404534,0.0002592682,0.0007727204,0.0002295789,0.0007112005,0.001191639],"category_scores_gemma":[0.001114509,0.0001992983,0.0002451078,0.0009714868,0.0003948531,0.000324876,0.0002769515,0.0004426413,0.0005674171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001861409,"about_ca_system_score_gemma":0.0002111782,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002233354,"about_ca_topic_score_gemma":0.0002573075,"domain_scores_codex":[0.9995136,0.0001618075,0.0000746881,0.0001010967,0.0001167359,0.00003203218],"domain_scores_gemma":[0.9995863,0.0001036187,0.0001224508,0.00002660193,0.00009726758,0.000063813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00519707,0.0005002505,0.3192089,0.001338376,0.0005940197,0.003587255,0.0006128899,0.0008930446,0.5546257,0.00232117,0.003446706,0.1076746],"study_design_scores_gemma":[0.0002359023,0.004385459,0.7294121,0.0003751068,0.0009636391,0.0326891,0.0008416561,0.01459722,0.1620639,0.003530036,0.05076244,0.0001434428],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9362893,0.03743653,0.009596158,0.0007294188,0.0005764334,0.0002876938,0.001625215,0.0004196489,0.01303959],"genre_scores_gemma":[0.9823886,0.002798938,0.01056841,0.00039251,0.0001307996,0.0001810238,0.000663823,0.00002661778,0.002849334],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001404534,"threshold_uncertainty_score":0.00568521,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01766280122872732,"score_gpt":0.2624094678879829,"score_spread":0.2447466666592555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}