{"id":"W4226094138","doi":"10.1080/15548627.2022.2039994","title":"Autophagopathies: from autophagy gene polymorphisms to precision medicine for human diseases","year":2022,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sinai Health System; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"National Institute of General Medical Sciences; Canceropôle Provence-Alpes-Côte d’Azur; National Institutes of Health; Agence Nationale de la Recherche","keywords":"Autophagy; Biology; Single-nucleotide polymorphism; SNP; Etiology; Gene; Bioinformatics; Genetics; Microbiome; Immunology; Medicine; Genotype; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003848537,0.0006552013,0.001458722,0.001570399,0.0003681223,0.001570806,0.0007653131,0.001351026,0.00531792],"category_scores_gemma":[0.00678998,0.0002122825,0.0008261344,0.001035312,0.001089408,0.001179573,0.0009875271,0.001666021,0.0008157304],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008778404,"about_ca_system_score_gemma":0.0009692564,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001437877,"about_ca_topic_score_gemma":0.001784153,"domain_scores_codex":[0.9984572,0.0008851548,0.0001009864,0.0003206632,0.0001871853,0.00004882817],"domain_scores_gemma":[0.9969297,0.002018604,0.0003545634,0.0002815432,0.0002675428,0.0001480961],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.001130474,0.0001098926,0.03897986,0.002585758,0.002913775,0.0007883555,0.0003256307,0.002350592,0.003984131,0.05302275,0.1246812,0.7691275],"study_design_scores_gemma":[0.000726168,0.0005763377,0.07907506,0.009483906,0.003038601,0.002763536,0.0007177626,0.006386401,0.00256758,0.4253429,0.469092,0.0002297146],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.02337579,0.7212153,0.05491244,0.1719667,0.005828187,0.00006651943,0.006439623,0.001097452,0.01509791],"genre_scores_gemma":[0.4532163,0.380796,0.07264667,0.06153369,0.01675416,0.0002542997,0.004306528,0.0002523737,0.01024002],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.00531792,"threshold_uncertainty_score":0.02035326,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02403793065368919,"score_gpt":0.3196115467439992,"score_spread":0.29557361609031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}