{"id":"W4226101007","doi":"10.1016/j.celrep.2021.110208","title":"Subcellular and regional localization of mRNA translation in midbrain dopamine neurons","year":2022,"lang":"en","type":"article","venue":"Cell Reports","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Drug Abuse; National Institute of Mental Health; National Institutes of Health; JPB Foundation; Fondation pour la Recherche Médicale; Institut National de la Santé et de la Recherche Médicale; National Institute of Neurological Disorders and Stroke; LabEx BRAIN; Pakistan Academy of Sciences; Centre National de la Recherche Scientifique; Aligning Science Across Parkinson’s; Agence Nationale de la Recherche; Eastern Health; Michael J. Fox Foundation for Parkinson's Research","keywords":"Translation (biology); Substantia nigra; Messenger RNA; Cell biology; Midbrain; Biology; Dopamine; Dopaminergic; Subcellular localization; Ribosome; RNA; Neuroscience; Biochemistry; Central nervous system; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009248046,0.0001556205,0.0002151602,0.0003991625,0.0002661245,0.0004241157,0.0001347761,0.0002663057,0.0006655805],"category_scores_gemma":[0.0001880178,0.0001531176,0.000229691,0.0001759352,0.0002541247,0.0002522288,0.0002135707,0.0003656104,0.000433756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003627564,"about_ca_system_score_gemma":0.0002013763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001289753,"about_ca_topic_score_gemma":0.002579746,"domain_scores_codex":[0.9998871,0.000008007189,0.00001029902,0.0000439716,0.0000291769,0.0000214287],"domain_scores_gemma":[0.9998596,0.00002377117,0.00003683149,0.00001450929,0.00003092986,0.00003441681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005095248,0.000005982325,0.0009626056,0.00002432257,0.000005199677,0.00006854615,0.00003277321,0.00002393711,0.9976071,0.00009818613,0.00001508844,0.001105221],"study_design_scores_gemma":[0.00002626471,0.0003746862,0.1967198,0.00002789541,0.00005066529,0.001802677,0.0004356373,0.00207189,0.7953715,0.0003448806,0.002752594,0.00002157873],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930798,0.002166177,0.002869585,0.00006889353,0.00001172514,0.000009736075,0.0004692735,0.00005057611,0.001274195],"genre_scores_gemma":[0.9921008,0.001065521,0.004361966,0.00004859974,0.00001432669,0.00003101414,0.0007610061,0.00003411972,0.001582657],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001289753,"threshold_uncertainty_score":0.002631962,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01094456077204769,"score_gpt":0.2044334126480581,"score_spread":0.1934888518760104,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}