{"id":"W4226102233","doi":"10.21203/rs.3.rs-1365421/v1","title":"Swift Formation Of Optimal Single Spheroids Towards In-Vitro 3-Dimensional Tumour Models","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Biochemical effects in animals","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Trent University; Cara; Nottingham Trent University","keywords":"Spheroid; In vivo; In vitro; Confocal microscopy; Cell biology; Cell culture; Cancer cell; Cell; Chemistry; Cellular pathology; Biology; Cancer; Pathology; Biophysics; Medicine; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007212328,0.0005393501,0.0004942896,0.0003911598,0.0003167294,0.0005460248,0.0002826074,0.0005152369,0.00210811],"category_scores_gemma":[0.0003772714,0.0003122983,0.000468506,0.0003210736,0.0002861278,0.0002935886,0.0005546712,0.0007241091,0.001847936],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002669806,"about_ca_system_score_gemma":0.0003461081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005064677,"about_ca_topic_score_gemma":0.001294487,"domain_scores_codex":[0.99963,0.00006714807,0.00006010453,0.00008759598,0.000110349,0.0000449049],"domain_scores_gemma":[0.9996197,0.00009300024,0.00006603057,0.00009709808,0.00008759182,0.00003651819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004104439,0.0000310287,0.0001846732,0.0001411622,0.000006731227,0.0001070775,0.00009406028,0.0009626147,0.9930987,0.0004538739,0.0004548083,0.004424256],"study_design_scores_gemma":[0.000008921797,0.0002013925,0.001562107,0.00003405642,0.00001515453,0.0002297832,0.00003278221,0.004327196,0.9808631,0.0002032083,0.01250728,0.00001492617],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.4289882,0.005299309,0.5404545,0.0005487364,0.0003974333,0.002147605,0.004585006,0.003179821,0.01439933],"genre_scores_gemma":[0.6033025,0.004001688,0.3762137,0.0001440721,0.00003578787,0.001942086,0.003930531,0.0005493448,0.009880183],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.00210811,"threshold_uncertainty_score":0.007052302,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09796094025177608,"score_gpt":0.3990447218885288,"score_spread":0.3010837816367527,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}