{"id":"W4226133497","doi":"10.1161/circ.144.suppl_1.11174","title":"Abstract 11174: Effect of APOCIII-L <sub>Rx</sub> on Lipoprotein Size and Particle Numbers Measured by NMR in Patients with Hypertriglyceridemia: Results of the AKCEA-APOCIII-L <sub>Rx</sub> Trial","year":2021,"lang":"en","type":"article","venue":"Circulation","topic":"Lipid metabolism and disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Heart Institute","funders":"","keywords":"Hypertriglyceridemia; Medicine; Internal medicine; Lipoprotein; Apolipoprotein B; Endocrinology; Triglyceride; Lipoprotein particle; Placebo; Nuclear medicine; Very low-density lipoprotein; Cholesterol; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001106355,0.0008317481,0.001831572,0.0002090586,0.00027847,0.0006867995,0.0004080227,0.0008028016,0.002582396],"category_scores_gemma":[0.0009536444,0.0002935844,0.0008240039,0.0002098855,0.0004695473,0.0004274226,0.0001837274,0.001581239,0.0005482354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003422918,"about_ca_system_score_gemma":0.0003920691,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004255597,"about_ca_topic_score_gemma":0.0007955335,"domain_scores_codex":[0.9996288,0.000206331,0.00003040994,0.00004637962,0.00003619766,0.00005189641],"domain_scores_gemma":[0.9994078,0.0001952888,0.0001354704,0.00005242275,0.00004514377,0.0001639162],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8968975,0.006467873,0.01485407,0.0006587602,0.002152201,0.0001785324,0.0001107536,0.0007284013,0.01648873,0.0001035678,0.001903254,0.05945636],"study_design_scores_gemma":[0.6449031,0.2731327,0.07074798,0.00008995752,0.003065255,0.0003907185,0.00009108495,0.001193809,0.003702296,0.0001369028,0.002493327,0.00005296365],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960757,0.002288176,0.00008580551,0.0001702842,0.00005438424,0.0001402408,0.0001642931,0.00002928817,0.0009918024],"genre_scores_gemma":[0.9962877,0.0009971106,0.0003665673,0.0003356041,0.0001728198,0.0001994848,0.0005447594,0.000009788367,0.001086228],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002582396,"threshold_uncertainty_score":0.008638978,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007802201376725035,"score_gpt":0.21763733400891,"score_spread":0.209835132632185,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}