{"id":"W4226154253","doi":"10.1016/j.bpj.2021.11.2761","title":"DNA methylation cues in nucleosome geometry, stability, and unwrapping","year":2022,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"","keywords":"Nucleosome; Cytosine; DNA methylation; Epigenetics; DNA; Biophysics; Chromatosome; Biology; CpG site; Methylation; Linker DNA; Histone; Computational biology; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002275698,0.0001946495,0.0002615048,0.0001562631,0.0003582288,0.0006946414,0.0005166166,0.0006473119,0.002172155],"category_scores_gemma":[0.0008511714,0.0005072438,0.0001551289,0.0001547704,0.0006039056,0.0007940851,0.000650539,0.0005893945,0.0004871181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004508553,"about_ca_system_score_gemma":0.00025947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001577994,"about_ca_topic_score_gemma":0.003520513,"domain_scores_codex":[0.9998418,0.00001764337,0.000008108867,0.00004855304,0.00004662501,0.00003730307],"domain_scores_gemma":[0.9997298,0.00007771925,0.0000496063,0.0000371757,0.00003797406,0.00006765051],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002025029,0.00001524326,0.00114341,0.00003346577,0.00000605365,0.00009815952,0.0000818636,0.0006266457,0.9907576,0.002607698,0.0001081994,0.004319205],"study_design_scores_gemma":[0.00005264518,0.0002148492,0.06908078,0.00001925375,0.00001717613,0.000373724,0.0004144788,0.01504293,0.9066792,0.00445228,0.003596313,0.00005638337],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9870077,0.001854575,0.007864961,0.0003056308,0.00006595914,0.000009241351,0.000112768,0.0000663832,0.002712792],"genre_scores_gemma":[0.9982279,0.0002304781,0.0006857157,0.00002405183,0.000007349958,0.000002864609,0.00004521526,0.00001257106,0.000763815],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002172155,"threshold_uncertainty_score":0.007266521,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01836232831318717,"score_gpt":0.2645607249283983,"score_spread":0.2461983966152111,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}