{"id":"W4226167898","doi":"","title":"Adverse Immunological Responses Against Non-viral Nanoparticle (NP) Delivery Systems in the Lung","year":2021,"lang":"en","type":"review","venue":"Research Explorer (The University of Manchester)","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Biotechnology and Biological Sciences Research Council","keywords":"Immune system; Genetic enhancement; Medicine; Immunology; Asthma; Gene delivery; Inflammation; Adverse effect; Biology; Gene; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003005514,0.0002850052,0.00111455,0.000499025,0.0003937987,0.00003850576,0.0008497969,0.0003497599,0.00008345571],"category_scores_gemma":[0.000266944,0.0001753246,0.000549936,0.0009071491,0.0007758708,0.0001648401,0.000500475,0.001470224,0.0002662103],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004374901,"about_ca_system_score_gemma":0.0008284951,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001809993,"about_ca_topic_score_gemma":0.000001393702,"domain_scores_codex":[0.9940307,0.003481397,0.0004772191,0.0004659455,0.0009913072,0.0005534478],"domain_scores_gemma":[0.9969688,0.001347762,0.0001978869,0.0009882391,0.0003838853,0.0001133921],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.004119137,0.004155069,0.001342812,0.06421185,0.003448667,0.02986659,0.1477445,0.0002254971,0.001179085,0.001022576,0.08041386,0.6622703],"study_design_scores_gemma":[0.000986488,0.000201337,0.0002973423,0.009655381,0.0003099989,0.0001096999,0.04514521,0.0001692135,0.00001720776,0.00000104152,0.9428758,0.0002312696],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1424507,0.8553025,0.000004551438,0.0003484609,0.0001221294,0.001482977,0.00001580128,0.00002434667,0.0002485457],"genre_scores_gemma":[0.02353824,0.9756955,0.00001833111,0.0001001835,0.0001202388,0.00001506795,0.00005307949,0.00002838148,0.0004309626],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8624619,"threshold_uncertainty_score":0.7149531,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1518054789588873,"score_gpt":0.3669741081161177,"score_spread":0.2151686291572305,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}