{"id":"W4226181264","doi":"10.3390/v14040817","title":"Novel Compound Inhibitors of HIV-1NL4-3 Vpu","year":2022,"lang":"en","type":"article","venue":"Viruses","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Tetherin; Virology; Biology; Function (biology); Infectivity; Virus; Cell biology; Viral replication","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001596654,0.0007481613,0.0007722474,0.0006536464,0.0002278733,0.0004465443,0.000503951,0.0003192715,0.002760745],"category_scores_gemma":[0.0001361699,0.0002415582,0.0004215213,0.0005095874,0.0001876047,0.0002326136,0.0002938308,0.0006992292,0.0007675151],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004691325,"about_ca_system_score_gemma":0.0003667528,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001242089,"about_ca_topic_score_gemma":0.00398193,"domain_scores_codex":[0.9998749,0.00001289543,0.000009180299,0.00002527173,0.00004346687,0.00003412469],"domain_scores_gemma":[0.9999378,0.00001462248,0.00001118861,0.000004973342,0.00001471612,0.00001678327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006468407,0.0007356031,0.00114219,0.000581302,0.0001033667,0.0005734589,0.0000903192,0.00232,0.9277261,0.0008734582,0.001727603,0.06347968],"study_design_scores_gemma":[0.002745152,0.01969796,0.01936906,0.0001622471,0.0005402525,0.004690131,0.0001562953,0.008604492,0.8760661,0.0008096566,0.0670372,0.0001213472],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9431214,0.02403103,0.005859996,0.0004521052,0.0001239081,0.0009840744,0.00325915,0.0006025333,0.0215658],"genre_scores_gemma":[0.9485213,0.02105813,0.007668509,0.0004660226,0.00007171765,0.0004772567,0.006097974,0.00006054947,0.01557862],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002760745,"threshold_uncertainty_score":0.009235561,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03650428705969067,"score_gpt":0.2825756127582735,"score_spread":0.2460713256985829,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}