{"id":"W4226258201","doi":"10.5167/uzh-213514","title":"Long-Term Outcomes With Nivolumab Plus Ipilimumab or Nivolumab Alone Versus Ipilimumab in Patients With Advanced Melanoma","year":2022,"lang":"en","type":"article","venue":"Zurich Open Repository and Archive (University of Zurich)","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":557,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Alberta Cancer Foundation","funders":"","keywords":"Nivolumab; Ipilimumab; Medicine; Melanoma; Internal medicine; Oncology; Cancer; Immunotherapy; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001606866,0.0003780538,0.0009139669,0.0002401679,0.0003712339,0.0004917469,0.0003043384,0.0004983171,0.001180367],"category_scores_gemma":[0.001093,0.0001221527,0.001259141,0.0001706793,0.0003383232,0.0004993451,0.0002885388,0.001154253,0.000256087],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004958506,"about_ca_system_score_gemma":0.000406563,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002600163,"about_ca_topic_score_gemma":0.0008286716,"domain_scores_codex":[0.9995517,0.0001927792,0.00003619715,0.00007187467,0.00006271687,0.00008476485],"domain_scores_gemma":[0.9991372,0.0001485802,0.000246008,0.00004183881,0.00004053764,0.0003859954],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.5998816,0.01332407,0.1473314,0.0008144372,0.003810676,0.0004218028,0.0001870909,0.004832537,0.01503904,0.0002417562,0.003345419,0.2107701],"study_design_scores_gemma":[0.05891692,0.6205429,0.3028628,0.0002142161,0.002991094,0.0007817604,0.0001435635,0.004014323,0.004087133,0.0007121981,0.004666073,0.00006702006],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926119,0.005728799,0.0002081815,0.000268713,0.0001101409,0.00008635761,0.0002483344,0.00001285113,0.000724683],"genre_scores_gemma":[0.9977098,0.0007917191,0.0001435633,0.0002706753,0.000169499,0.00008758435,0.0003837124,0.000001978776,0.0004414387],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001606866,"threshold_uncertainty_score":0.008498013,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01238624569484616,"score_gpt":0.2277708140967711,"score_spread":0.2153845684019249,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}