{"id":"W4226270647","doi":"10.4103/glioma.glioma_1_22","title":"The diverse landscape of histone-mutant pediatric high-grade gliomas","year":2022,"lang":"en","type":"article","venue":"Glioma","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Epigenetics; Histone; Glioma; Medicine; Mutant; Biology; Cancer research; Bioinformatics; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002391803,0.0002416273,0.0003001584,0.0006331559,0.0001662151,0.0006050264,0.0002058148,0.0003161691,0.0006414216],"category_scores_gemma":[0.0003052849,0.00008763711,0.0001764378,0.000553344,0.0002475114,0.0004012224,0.0002842227,0.0003480381,0.0002456419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004511139,"about_ca_system_score_gemma":0.000302616,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005396681,"about_ca_topic_score_gemma":0.0009738809,"domain_scores_codex":[0.9998282,0.00002697468,0.00001478646,0.00003020067,0.00006274785,0.00003708513],"domain_scores_gemma":[0.999915,0.00001756358,0.00003144682,0.000002953301,0.00001729309,0.00001577464],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0008694991,0.00007484954,0.06594308,0.002284642,0.0002259303,0.01258369,0.0007001696,0.001791397,0.2096194,0.01225949,0.01038895,0.6832589],"study_design_scores_gemma":[0.00006767487,0.001219341,0.3196111,0.001034211,0.0007128438,0.1359849,0.001941441,0.001592462,0.1072295,0.01710902,0.4133948,0.0001026344],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.3373803,0.6369507,0.006001665,0.003999205,0.0001658312,0.00004023163,0.0009459015,0.000235127,0.01428095],"genre_scores_gemma":[0.5999035,0.3922147,0.003408866,0.0009994967,0.0002887701,0.00003368884,0.001110296,0.00004237642,0.001998243],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.0006414216,"threshold_uncertainty_score":0.003273129,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01361130905575042,"score_gpt":0.2713522912018594,"score_spread":0.257740982146109,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}