{"id":"W4226342731","doi":"10.2337/db21-0803","title":"Glucose-Dependent miR-125b Is a Negative Regulator of β-Cell Function","year":2022,"lang":"en","type":"article","venue":"Diabetes","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; University of Alberta","funders":"Imperial College London; National Institute of Diabetes and Digestive and Kidney Diseases; Medical Research Council; Diabetes UK; Wellcome Trust","keywords":"Regulator; Function (biology); Negative regulator; Cell function; Internal medicine; Chemistry; Biology; Cell biology; Cell; Medicine; Biochemistry; Signal transduction; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001615389,0.0006278483,0.0004632196,0.0004547917,0.0002751574,0.0006286471,0.0002792343,0.0003725379,0.001168288],"category_scores_gemma":[0.0002336503,0.0002523919,0.0004030053,0.0003894189,0.0002071285,0.0001497491,0.0003129388,0.0005016575,0.001027831],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003964733,"about_ca_system_score_gemma":0.0002589794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008226666,"about_ca_topic_score_gemma":0.0008906221,"domain_scores_codex":[0.9997293,0.00001864125,0.00002562688,0.00006793701,0.0001325293,0.0000259533],"domain_scores_gemma":[0.9998832,0.0000114606,0.00005012555,0.0000106386,0.00002055158,0.00002399412],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001575868,0.00001863297,0.001090979,0.0001458171,0.00003041936,0.0001434434,0.00001353581,0.0001219026,0.9875067,0.0002334662,0.0005922616,0.009945239],"study_design_scores_gemma":[0.00005390447,0.0002310568,0.02791499,0.0000562364,0.0001199873,0.001375811,0.00003066122,0.002443906,0.9169794,0.0003357672,0.05043161,0.00002671793],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8579895,0.06547067,0.03627077,0.001025398,0.0005703503,0.000275607,0.009723526,0.002528778,0.02614537],"genre_scores_gemma":[0.9587963,0.01164098,0.01322489,0.0006381698,0.00006424541,0.0001472678,0.008949909,0.000222822,0.006315554],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001168288,"threshold_uncertainty_score":0.003908277,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0109312959148863,"score_gpt":0.2214421931451565,"score_spread":0.2105108972302702,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}