{"id":"W4226407587","doi":"10.12667/mhc.29.42","title":"Immune-mediated thrombotic thrombocytopenic purpura and HLA","year":2022,"lang":"en","type":"article","venue":"Major Histocompatibility Complex","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Tula Foundation","funders":"","keywords":"ADAMTS13; Thrombotic thrombocytopenic purpura; Human leukocyte antigen; Von Willebrand factor; Immune system; Immunology; Medicine; Antigen; Platelet","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000661831,0.0003604726,0.0007865593,0.0001810899,0.001318785,0.00003670927,0.0007319217,0.00007054224,0.02843015],"category_scores_gemma":[0.0001134116,0.0003786451,0.0001874462,0.0003165609,0.0005172904,0.0001138049,0.001180713,0.0004429969,0.0005519809],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004997067,"about_ca_system_score_gemma":0.0001204714,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008626534,"about_ca_topic_score_gemma":0.0001387232,"domain_scores_codex":[0.9965535,0.001012192,0.0008665943,0.0008096376,0.0001647208,0.000593391],"domain_scores_gemma":[0.9980278,0.0004340246,0.0003100371,0.001083745,0.00007653953,0.00006782993],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0008776396,0.002968436,0.1825705,0.000472308,0.0009106208,0.00004096245,0.002935907,0.0001245831,0.7065701,0.00915963,0.09019611,0.003173249],"study_design_scores_gemma":[0.004877691,0.0006524383,0.8672231,0.00002455555,0.0001626573,0.0001831822,0.001356813,0.0002783065,0.0008000914,0.002459288,0.1211622,0.000819701],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894818,0.003303084,0.00006716917,0.0005971764,0.0008096455,0.002419078,0.0005492129,0.0003500738,0.002422784],"genre_scores_gemma":[0.9971658,0.000003112963,0.0001198439,0.0002845397,0.00002062784,0.0004993174,0.001171351,0.00003685102,0.0006985553],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.70577,"threshold_uncertainty_score":0.9999813,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03264048993766581,"score_gpt":0.2631317802015113,"score_spread":0.2304912902638455,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}