{"id":"W4226434158","doi":"10.1097/dss.0000000000003238","title":"Efficacy and Safety of a New Resilient Hyaluronic Acid Filler in the Correction of Moderate-to-Severe Dynamic Perioral Rhytides: A 52-Week Prospective, Multicenter, Controlled, Randomized, Evaluator-Blinded Study","year":2021,"lang":"en","type":"article","venue":"Dermatologic Surgery","topic":"Facial Rejuvenation and Surgery Techniques","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cosmedica","funders":"","keywords":"Medicine; Patient satisfaction; Wrinkle; Hyaluronic acid; Randomized controlled trial; Adverse effect; Multicenter study; Clinical endpoint; Clinical trial; Dermatology; Surgery; Dentistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007286149,0.00190273,0.003626128,0.0007621414,0.0007128362,0.001162378,0.001701586,0.002761792,0.003209967],"category_scores_gemma":[0.003867992,0.001063206,0.001955818,0.0005365177,0.00247909,0.00166363,0.000500945,0.002112856,0.000776895],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005294999,"about_ca_system_score_gemma":0.001313156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000360276,"about_ca_topic_score_gemma":0.0006719473,"domain_scores_codex":[0.9960187,0.002324173,0.0003838042,0.0006249837,0.0003811197,0.0002672231],"domain_scores_gemma":[0.9965365,0.001216894,0.000961072,0.0004292166,0.0003083505,0.0005479575],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8929615,0.06176426,0.001141662,0.0008435925,0.0007086344,0.00006846532,0.0001772947,0.0003882624,0.02108133,0.00008637809,0.0003161719,0.02046243],"study_design_scores_gemma":[0.5216187,0.4722579,0.002289097,0.00002623561,0.0003911009,0.00004792749,0.00003406086,0.0004524907,0.002438792,0.00005359792,0.0003657277,0.00002430622],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892619,0.001724363,0.00144079,0.0001671365,0.000258951,0.006124774,0.0003419906,0.00009305296,0.0005871596],"genre_scores_gemma":[0.9877753,0.001074353,0.003478599,0.0004059444,0.0006725966,0.005247958,0.0002975169,0.00003245448,0.001015268],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007286149,"threshold_uncertainty_score":0.03853327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03074750833315196,"score_gpt":0.3196746680569223,"score_spread":0.2889271597237703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}