{"id":"W4226460803","doi":"10.3389/fpsyt.2022.856867","title":"Aquaporin-4, Connexin-30, and Connexin-43 as Biomarkers for Decreased Objective Sleep Quality and/or Cognition Dysfunction in Patients With Chronic Insomnia Disorder","year":2022,"lang":"en","type":"article","venue":"Frontiers in Psychiatry","topic":"Sleep and related disorders","field":"Psychology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Anhui Medical University; National Natural Science Foundation of China","keywords":"Connexin; Insomnia; Cognition; Medicine; Chronic insomnia; Sleep quality; Psychiatry; Clinical psychology; Sleep disorder; Psychology; Internal medicine; Bioinformatics; Biology; Gap junction; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004566998,0.0003148454,0.0004026823,0.0005180958,0.0002922323,0.00002524834,0.000129612,0.0002339207,0.0005057759],"category_scores_gemma":[0.00006665772,0.0002899598,0.0000647031,0.0005816725,0.0002410886,0.0001474121,0.00005345581,0.0004304043,0.000006828293],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002222834,"about_ca_system_score_gemma":0.000161311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000657152,"about_ca_topic_score_gemma":0.0007637659,"domain_scores_codex":[0.9975716,0.0004268565,0.0005095218,0.0007692255,0.0002419411,0.0004808228],"domain_scores_gemma":[0.9991447,0.0001432619,0.0002592317,0.0002737022,0.00005524433,0.0001239014],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01726678,0.001617725,0.9492658,0.00007738106,0.0008092087,0.000003929473,0.001503965,0.00005151306,0.00000175885,0.001372657,0.007477278,0.02055204],"study_design_scores_gemma":[0.05484013,0.003395334,0.9029157,0.00007475561,0.0002842433,0.000007343643,0.02469313,0.0004219374,0.000001563505,0.009856438,0.002802411,0.0007070344],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9806303,0.00423643,0.002644517,0.0004847661,0.007893606,0.002092255,0.0001328358,0.0000674919,0.001817767],"genre_scores_gemma":[0.9969411,0.00007674927,0.000977389,0.000663311,0.0000635356,0.0007730426,0.0003145504,0.00006277842,0.0001275648],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0463501,"threshold_uncertainty_score":0.9999552,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007438872403413463,"score_gpt":0.2613628063231197,"score_spread":0.2539239339197062,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}