{"id":"W4228996482","doi":"10.1139/cjm-2022-0024","title":"Sequential markerless genetic manipulations of species from the <i>Neisseria</i> genus","year":2022,"lang":"en","type":"article","venue":"Canadian Journal of Microbiology","topic":"Protist diversity and phylogeny","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Armand Frappier Museum; Institut National de la Recherche Scientifique","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds de recherche du Québec – Nature et technologies; Canadian Institutes of Health Research; Armand-Frappier Foundation","keywords":"Biology; Neisseria; Genetics; Neisseria gonorrhoeae; Gene; Selection (genetic algorithm); Neisseria meningitidis; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004068472,0.000547952,0.0004593677,0.0004603313,0.0003061736,0.0005247932,0.0007000957,0.0004082857,0.00078786],"category_scores_gemma":[0.0004738812,0.0003429112,0.0004721209,0.0003279049,0.0003979757,0.0003266092,0.0008387424,0.00106125,0.0005656069],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003940108,"about_ca_system_score_gemma":0.0003714012,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008885945,"about_ca_topic_score_gemma":0.0019701,"domain_scores_codex":[0.9995566,0.00006570779,0.00007956044,0.0001084839,0.0001223043,0.00006738357],"domain_scores_gemma":[0.9994864,0.00008021851,0.0002003462,0.000143119,0.00004556733,0.00004440314],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001825445,0.000007646668,0.00009596931,0.00002223465,0.000002402494,0.00002917863,0.00002513749,0.0000157062,0.9984733,0.0001012671,0.00001629792,0.001192648],"study_design_scores_gemma":[0.000005142777,0.0001011643,0.001848738,0.00001225826,0.00002195502,0.000434804,0.00004468039,0.0002242947,0.9928637,0.00005388394,0.004380657,0.00000888699],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9029009,0.001491769,0.08878914,0.0002430948,0.0001289732,0.0005282927,0.001617267,0.0007968083,0.003503739],"genre_scores_gemma":[0.8905673,0.001669082,0.09945942,0.0001636055,0.00002179282,0.0003634746,0.003314946,0.0005444302,0.003895848],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008885945,"threshold_uncertainty_score":0.002858818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01441236546299335,"score_gpt":0.1901551703278839,"score_spread":0.1757428048648905,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}