{"id":"W4228997704","doi":"10.3390/biomedicines10051078","title":"Remodeling of the Dermal Extracellular Matrix in a Tissue-Engineered Psoriatic Skin Model by n-3 Polyunsaturated Fatty Acids","year":2022,"lang":"en","type":"article","venue":"Biomedicines","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut universitaire de cardiologie et de pneumologie de Québec; Université Laval","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Université Laval","keywords":"Extracellular matrix; Chemistry; Lipidome; Western blot; Polyunsaturated fatty acid; Molecular biology; Psoriasis; Biochemistry; Lipidomics; Fatty acid; Biology; Immunology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000219332,0.000315963,0.0002489542,0.0002599031,0.0001437977,0.0002313533,0.0001394646,0.0002867313,0.0008892078],"category_scores_gemma":[0.00006552722,0.0001547991,0.0003341839,0.0001815403,0.0001766306,0.0002332406,0.0001434411,0.0007130278,0.0002202497],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001195436,"about_ca_system_score_gemma":0.0001715459,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003613037,"about_ca_topic_score_gemma":0.000472696,"domain_scores_codex":[0.9998069,0.00003267221,0.00001700578,0.00003487211,0.00008250659,0.00002605298],"domain_scores_gemma":[0.9999002,0.00001115664,0.00002610789,0.00001334229,0.00001509511,0.00003406761],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001697094,0.0001225639,0.00008484269,0.00003505553,0.00000520332,0.00006663865,0.00001526649,0.00009173821,0.9985918,0.00003990789,0.00002174025,0.0007553013],"study_design_scores_gemma":[0.00005303145,0.002056974,0.004713821,0.00001628872,0.00004619811,0.0005731191,0.0001125717,0.003878929,0.9860939,0.00007568008,0.002367294,0.00001219536],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931804,0.0007177057,0.004382838,0.00006345021,0.00006923867,0.00008156116,0.0002368806,0.00005590508,0.001212062],"genre_scores_gemma":[0.9908375,0.0006822597,0.005599963,0.00006406447,0.0000104861,0.00009633978,0.0002480676,0.00001069137,0.002450633],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008892078,"threshold_uncertainty_score":0.002974689,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01203030753092993,"score_gpt":0.2366965885511329,"score_spread":0.224666281020203,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}