{"id":"W4228997704","doi":"10.3390/biomedicines10051078","title":"Remodeling of the Dermal Extracellular Matrix in a Tissue-Engineered Psoriatic Skin Model by n-3 Polyunsaturated Fatty Acids","year":2022,"lang":"en","type":"article","venue":"Biomedicines","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut universitaire de cardiologie et de pneumologie de Québec; Université Laval","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Université Laval","keywords":"Extracellular matrix; Chemistry; Lipidome; Western blot; Polyunsaturated fatty acid; Molecular biology; Psoriasis; Biochemistry; Lipidomics; Fatty acid; Biology; Immunology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002398503,0.0001815997,0.0003027355,0.0001727113,0.0001604817,0.000003406137,0.0002873232,0.0001297376,0.0001873799],"category_scores_gemma":[0.00002918532,0.0001283746,0.00007532406,0.000525091,0.00009790308,0.00003871736,0.00009727984,0.0001805689,0.0000122606],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005952885,"about_ca_system_score_gemma":0.00006899691,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001569598,"about_ca_topic_score_gemma":0.000008442228,"domain_scores_codex":[0.9988398,0.0001904503,0.0003718376,0.0002318382,0.00008444446,0.0002816528],"domain_scores_gemma":[0.9994764,0.00006271054,0.0001255113,0.0002882214,0.00002983741,0.0000173363],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001435809,0.0001507236,0.0007192672,0.00002251129,0.00008476074,0.00000535356,0.0007455909,0.001074571,0.9882039,0.00006544767,0.001740135,0.007044156],"study_design_scores_gemma":[0.014115,0.0006411152,0.009739144,0.0001820779,0.0007472783,0.0002744424,0.00228225,0.02773461,0.9006171,0.0005276196,0.0421937,0.0009457148],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.960591,0.0365204,0.0007676873,0.0006191584,0.0009460575,0.000307759,0.0001680888,0.00004038573,0.00003949541],"genre_scores_gemma":[0.9958082,0.00008762167,0.0002065456,0.00003442336,0.00003179935,0.00004673242,0.0002391262,0.00001867477,0.003526872],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08758686,"threshold_uncertainty_score":0.5234963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01203030753092993,"score_gpt":0.2366965885511329,"score_spread":0.224666281020203,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}