{"id":"W4229002976","doi":"10.1371/journal.pone.0268095","title":"Prevalence of arps10, fd, pfmdr-2, pfcrt and pfkelch13 gene mutations in Plasmodium falciparum parasite population in Uganda","year":2022,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Malaria Research and Control","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Minority Health and Health Disparities; National Institute of Dental and Craniofacial Research; National Institute of Neurological Disorders and Stroke; International Development Research Centre; National Heart, Lung, and Blood Institute; Fogarty International Center; National Institutes of Health","keywords":"Plasmodium falciparum; Biology; Apicoplast; Malaria; Artemether/lumefantrine; Single-nucleotide polymorphism; Population; Sanger sequencing; High Resolution Melt; Genetics; Genotype; Virology; Artemisinin; Parasite hosting; Artesunate; DNA sequencing; Gene; Medicine; Apicomplexa; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003730879,0.0002052549,0.0001889111,0.0007523546,0.0003596089,0.0003758524,0.0002367172,0.0003134888,0.001114239],"category_scores_gemma":[0.001123187,0.0002668699,0.0001297863,0.0006353763,0.0005315707,0.0002859238,0.0003015214,0.0002246392,0.0001483605],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002219643,"about_ca_system_score_gemma":0.0001848986,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003051633,"about_ca_topic_score_gemma":0.004186212,"domain_scores_codex":[0.999624,0.00008549566,0.00004984969,0.00008981016,0.00008583119,0.00006501476],"domain_scores_gemma":[0.9995665,0.00006636827,0.00022911,0.00002326892,0.00006452676,0.00005016644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00016621,0.0000356922,0.9826817,0.00009226255,0.0000291048,0.0009971347,0.001065301,0.00007356043,0.004677405,0.0000586528,0.0002056002,0.009917375],"study_design_scores_gemma":[0.000003810352,0.0001713542,0.9937086,0.00003704527,0.00002329556,0.003424094,0.0008989929,0.0000898845,0.0009629296,0.0000291795,0.0006435231,0.000007330511],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999313,0.0003182574,0.00005113101,0.00001379678,0.00000216475,0.000005001622,0.00008267648,0.000002494545,0.0002116074],"genre_scores_gemma":[0.9993281,0.0003251469,0.00008457286,0.000008812089,0.00000223558,0.00000560084,0.00008063514,8.914598e-7,0.0001638947],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003051633,"threshold_uncertainty_score":0.006067753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03711906646469807,"score_gpt":0.280372826623866,"score_spread":0.2432537601591679,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}