{"id":"W4229003386","doi":"10.1016/j.anireprosci.2022.106990","title":"TBBPA downregulates thyroid receptor and estrogen receptor mRNA levels in goldfish gonadal tissue","year":2022,"lang":"en","type":"article","venue":"Animal Reproduction Science","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; St. George’s University","keywords":"Tetrabromobisphenol A; Endocrine system; Endocrine disruptor; Estrogen receptor; Thyroid; Endocrinology; Internal medicine; Hormone; Receptor; In vivo; Biology; Thyroid hormone receptor; Sex steroid; Estrogen; Benzhydryl compounds; Chemistry; Bisphenol A; Steroid; Medicine; Fire retardant","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001254229,0.0002869985,0.0003725675,0.0004398245,0.0004265117,0.0004882812,0.0002065563,0.0003521031,0.003729464],"category_scores_gemma":[0.0001955147,0.0004378903,0.0005197035,0.0002386304,0.0005554889,0.0002557293,0.0002931833,0.0007193887,0.0006197321],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006069234,"about_ca_system_score_gemma":0.0005728536,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009128337,"about_ca_topic_score_gemma":0.01192864,"domain_scores_codex":[0.9998038,0.00001195549,0.00001440156,0.00006629855,0.00003963457,0.00006382562],"domain_scores_gemma":[0.9998413,0.00002349732,0.00003237501,0.00002242669,0.00003359745,0.00004672773],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002636708,0.00001777567,0.0006277643,0.00003289707,0.00001100786,0.00003626036,0.00002665581,0.00001604555,0.9981902,0.00004267836,0.00004785551,0.0006870537],"study_design_scores_gemma":[0.00006249646,0.0004599816,0.04574065,0.00001420629,0.0000906243,0.0001832551,0.0002658004,0.0004385978,0.9489272,0.00009109977,0.003711373,0.00001477594],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955903,0.001052608,0.001322673,0.0001953469,0.00009580845,0.00001508982,0.00049642,0.00007543327,0.001156387],"genre_scores_gemma":[0.9754906,0.001126167,0.001367159,0.0002438834,0.00003352615,0.00006798095,0.001218148,0.00007291176,0.02037965],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009128337,"threshold_uncertainty_score":0.01815039,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0153846640320399,"score_gpt":0.2560119062280378,"score_spread":0.2406272421959979,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}