{"id":"W4229004609","doi":"10.1002/cam4.4789","title":"Association of anticoagulant use with clinical outcomes from crizotinib in <i>ALK</i><scp><i>‐</i></scp> and <i>ROS1</i>‐rearranged advanced non‐small cell lung cancers: A retrospective analysis of <scp>PROFILE</scp> 1001","year":2022,"lang":"en","type":"article","venue":"Cancer Medicine","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Cancer Center, University of Colorado; Pfizer","keywords":"Crizotinib; ROS1; Medicine; Internal medicine; Retrospective cohort study; Surrogate endpoint; Gastroenterology; Oncology; Hazard ratio; Lung cancer; Clinical trial; Anaplastic lymphoma kinase; Confidence interval; Cancer; Adenocarcinoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001122524,0.0001565089,0.0003656571,0.000413877,0.0001844937,0.0005699584,0.0003088073,0.0003645961,0.000814144],"category_scores_gemma":[0.002494266,0.0001535924,0.0006339744,0.0006024681,0.0002125511,0.000293022,0.0002366312,0.0005860246,0.0001365973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003800316,"about_ca_system_score_gemma":0.0002478094,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008733427,"about_ca_topic_score_gemma":0.001340978,"domain_scores_codex":[0.9988678,0.000278098,0.0002252245,0.000292699,0.0002393158,0.00009698248],"domain_scores_gemma":[0.9965413,0.0008028059,0.001937509,0.0001891927,0.0001822708,0.0003469918],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001993891,0.00004395428,0.9943299,0.00002299847,0.000351903,0.00008340627,0.00002215334,0.0001498798,0.0008218164,0.00001725031,0.00008921091,0.002073542],"study_design_scores_gemma":[0.00006878073,0.0006128746,0.9977539,0.000005335894,0.000194457,0.0004656716,0.00002593044,0.0003561975,0.0003001733,0.00001968557,0.0001916505,0.000005410338],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987066,0.0005725285,0.00005108526,0.00001772332,0.000002607345,0.00000810381,0.0003442374,0.000001829189,0.0002953025],"genre_scores_gemma":[0.999398,0.00009620826,0.00001991322,0.0000131664,0.000005907808,0.0000077526,0.0004023191,0.000001295392,0.00005534389],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001122524,"threshold_uncertainty_score":0.005936503,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02218792812441873,"score_gpt":0.331051219277176,"score_spread":0.3088632911527572,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}