{"id":"W4229019529","doi":"10.1038/s41467-022-30087-z","title":"Candida albicans evades NK cell elimination via binding of Agglutinin-Like Sequence proteins to the checkpoint receptor TIGIT","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Azrieli Foundation; Israel Science Foundation; German-Israeli Foundation for Scientific Research and Development; Deutsches Krebsforschungszentrum; Israel Cancer Research Fund","keywords":"TIGIT; Candida albicans; Biology; Immune system; Immunology; Innate immune system; Antibody; Immunity; Immunotherapy; Microbiology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008057528,0.0002446185,0.0001556626,0.00009656927,0.00009614192,0.0002228048,0.0001957792,0.000201539,0.0009615344],"category_scores_gemma":[0.00008782208,0.00006281806,0.0001986291,0.00006199005,0.0001353641,0.0001206096,0.0001702911,0.0004819174,0.0003239886],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001752075,"about_ca_system_score_gemma":0.0001624573,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002690494,"about_ca_topic_score_gemma":0.0002877569,"domain_scores_codex":[0.9999076,0.00001952917,0.000005861333,0.00001630107,0.00002061577,0.00003006197],"domain_scores_gemma":[0.9999707,0.000004919985,0.000007966619,0.000003948142,0.00000305099,0.00000935528],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001435213,0.00002248573,0.0001797882,0.0000273552,0.000003856548,0.00004787988,0.000006062894,0.00008493434,0.9976191,0.0001321111,0.0000612358,0.00167159],"study_design_scores_gemma":[0.00004087821,0.0004912241,0.005049017,0.000007453027,0.00001062591,0.0005827881,0.00002520538,0.00178294,0.9890364,0.0001062616,0.002863535,0.000003643143],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928097,0.001980071,0.002263836,0.0001723305,0.0000422328,0.00001595103,0.00009002725,0.0000793841,0.002546431],"genre_scores_gemma":[0.9968051,0.0004950863,0.0009654005,0.00008072233,0.000009886162,0.00001166623,0.0001065026,0.000007602853,0.001518029],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009615344,"threshold_uncertainty_score":0.003216684,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02275407292768471,"score_gpt":0.2772293947750198,"score_spread":0.2544753218473351,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}